Abstract：Objective: To investigate the relationship between the stent implatation and the changes of microenvironment of the bile duct. Methods: Fifteen cases with low malignant obstruction of bile duct were implanted with metallic stent. The bile was gathered before and after the stenting, and then the volume of AMS, LPS, pH value was measured, and the germiculture was performed. Oral 99mTc was also performed after the biliary stenting. Results: The AMS/LPS was higher than before biliary stenting, and pH value was lower than before as well. The result of germiculture was positive. Oral 99mTc proved that the enteric bile reflux existed. Conclusion: Biliary internal environment was changed apparently after metallic stent implanted through ampullae. The enteric bile reflux and the pancreatic bile reflux should be considered when the biliary stent has to be implanted through ampullae.
2009, Vol. 20 
