Abstract：Objective: To investigate the CT characteristics of periventricular leukomalacia. Methods: The clinical CT findings of 83 cases of periventricular leukomalacia were retrospectively analyzed. Results: Fourteen cases of the softening lesions type near cerebral ventricle included 5 cases of beside the bilateral occipital horn, 2 cases of body and anterior horn near posterior horn of right lateral ventricle, 3 cases of beside left lateral ventricle body, 2 cases of near occipital horn, and accompanied by white matter reduction beside softening lesions and cortical gray matter thinning. 69 cases of the diffuse white matter reduction type included 39 cases of near the occipital horn, 15 cases of anterior horn near posterior horn, 15 cases of diffuse white matter reduction. There were 7 cases of merging demyelinating lesions type and 19 cases of agenesis of corpus callosum. CT showed mottling or funicular malacia lesions around cerebral ventricle. Individual cases presented the ball cystic changes. The white matter capacity near anterior horn or posterior horn of dual lateral ventricle reduced, severely centrum semiovale had residual small area white matter. The occipital horns showed right angle shaped enlargement, the stiff edge, gray matter layer approaching the outer edge of the cerebral ventricle. Statistical results confirmed the production history of different pregnancy gestational age have a difference for the distribution of the lesion types(χ2=52.28, P＜0.05), the distribution position of diffuse white matter reduction have a difference with production history of pregnancy gestational age(χ2=25.89, P＜0.05). Brain white matter injury severity in perinatal related to gestational age, smaller gestational age in pregnancy, the more severe white matter injury. Conclusions: Periventricular leukomalacia have certain feature, pathological anatomy morphology of the cerebral white matter injury can been clearly displayed by CT.
2015, Vol. 26 
