Abstract：Objective: To investigate the enhancement pattern and parameters of contrast enhanced ultrasound(CEUS) in gallbladder adenomyomatosis. Methods: Thirty pathologically proven gallbladder adenomyosis in 30 patients who had undergone CEUS preoperatively were included in this study. Various contrast enhancement patterns and parameters were retrospectively analyzed. Results: Twenty-five lesions showed hyper-enhancement during the arterial phase and 5 lesions showed iso-enhancement. As to the pattern of intralesional vascularity, 9 lesions showed peripheral rim-like hyper-enhancement（30%, 9/30）. The contrast agent entered the mucosa firstly and then theserosa of the gallbladder wall. The arrival time of contrast agent to the lesion was (13.83±3.38) s and the washout time was (56.29±28.91) s. Preoperatively, two readers using conventional ultrasound made 5 correct diagnosis of gallbladder adenomyomatosis among the all 30 cases(16.7%, 5/30) whereas, using CEUS they made 26 correct ones(86.7%, 26/30). Besides, 11 lesions which were poorly defined using conventional ultrasound were well defined using CEUS. Conclusions: Enhancement patterns and parameters of CEUS may be useful in the noninvasive diagnosis of gallbladder adenomyomatosis.
王金环，徐辉雄，刘琳娜，郑曙光，孙丽萍，郭乐杭. 胆囊腺肌增生症的超声造影表现分析[J]. 中国临床医学影像杂志, 2016, 27(3): 177-179.
WANG Jin-huan, XU Hui-xiong, LIU Lin-na, ZHENG Shu-guang, SUN Li-ping, GUO Le-hang. The imaging analysis of gallbladder adenomyomatosis on contrast-enhanced ultrasound. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(3): 177-179.
[1]Stuenll H, Buckley O, Geoghegan T, et al. Imaging of adenomyomatosis of the gallbladder[J]. J Med Imaging Radiat Oncol, 2008, 522(2): 109-117.
[2]陈灏珠，林果为. 实用内科学[M]. 13版. 北京：人民卫生出版社，2009：2158.
[3]Liu LN, Xu HX, Lu MD, et al. Contrast-enhanced ultrasound in the diagnosis of gallbladder diseases: a multi-center experience[J]. PLoS One, 2012, 7(10): e48371.
[4]Xie XH, Xu HX, Xie XY, et al. Differential diagnosis between benign and malignant gallbladder diseases with real-time contrast-enhanced ultrasound[J]. Eur Radiol, 2010, 20(1): 239-248.
[5]Zheng SG, Xu HX, Liu LN, et al. Contrast-enhanced ultrasound versus conventional ultrasound in the diagnosis of polypoid lesion of gallbladder: a multi-center study of dynamic microvascularization[J]. Clin Hemorheol Micro, 2013, 55(3): 359-374.
[6]殷雷，邱法波，吴昌亮，等. 中国近30年胆囊腺肌增生症流行病学特征及诊治经验[J]. 中国现代医学杂志，2012，22（18）：67-68.
[7]费翔，刘强，吕发勤，等. 超声造影在胆囊占位性病变鉴别诊断中的临床应用[J]. 中华医学超声杂志：电子版，2011，8（12）：2552.
[8]谢晓华，徐辉雄，谢晓燕，等. 超声造影新技术对胆囊良恶性疾病的鉴别诊断价值[J]. 中华肝胆外科杂志，2009，9（15）：643.
[9]王松，严昆，杨薇，等. 肝脏炎性病灶超声造影定量分析[J]. 中华医学超声杂志：电子版，2013，10（5）：26.
