Abstract：Objective: To explore the feasibility of iSTIC in evaluation of left ventricular wall volumes in normal fetuses. Methods: Real Time three-dimensional echocardiography were performed in 124 normal fetuses from 20 to 36 weeks gestation with Phillips iU22G4 ultrasonic diagnostic instrument. The images were analyzed by QLAB software with Stacked contours method for measuring left ventricular end-diastolic interior volume and peripheral volume. The different value between interior volume and peripheral volume was the left ventricular wall volume. The correlation between fetal left ventricular wall volume and gestational age was analyzed. The intraclass correlation coefficient(ICC) was used to evaluate the agreement of inter-observer and intra-observer. Results: The iSTIC volumes of 16 fetuses were excluded from the study because of the poor image quality. There was a significant correlation between left ventricular wall volume and gestational age(P<0.05). The reproducibility of intra-observer and inter-observer evaluated by ICC were better(ICC of intraobserver was 0.978, 95% CI: 0.947~0.991, ICC of interobserver was 0.927, 95% CI: 0.825~0.970). Conclusion: The iSTIC technique is a simple and feasible modality to determine the fetal left ventricular wall volumes in normal fetuses. This method may become a new way for evaluating fetal heart development.
王 超，解丽梅. 应用iSTIC技术评估正常胎儿左心室室壁体积的研究[J]. 中国临床医学影像杂志, 2016, 27(5): 363-366.
WANG Chao, XIE Li-mei. A study on left ventricular wall volume using intelligent spatiotemporal image correlation in normal fetuses. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(5): 363-366.
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