1. Department of Radiology, Yueqing People’s Hospital of Zhejiang, Yueqing Zhejiang 325600, China;
2. Department of Radiology, Wenzhou People’s Hospital of Zhejiang, Wenzhou Zhejiang 325000, China
摘要目的：探讨原发性骨淋巴瘤（Primary bone lymphoma，PBL）的影像表现特点。方法：回顾性分析经病理证实26例PBL患者的X线平片、CT和MRI表现。结果：26例中男14例，女12例，年龄20～73岁，平均（40.7±5.8）岁。26例中位于颅骨7例，股骨5例，肱骨4例，脊柱4例，锁骨2例，髂骨2例，胫骨1例，腓骨1例。X线和CT表现：溶骨型21例，混合型3例，硬化型1例，囊状型1例。伴病理性骨折3例，轻度骨膜反映3例，有较明显的软组织肿块21例。MRI检查7例：信号均匀3例，信号不均匀4例；病灶于T1WI上呈等、稍低信号，T2WI上呈稍高信号5例，呈等信号2例。增强扫描7例：肿瘤中度强化5例，显著强化1例，轻度强化1例。结论：PBL影像学有一定的特点，骨破坏多见于溶骨型，增强后以中度强化为主，常伴有明显的软组织肿块。
Abstract：Objective: To investigate the imaging characteristics of primary bone lymphoma(PBL). Methods: The X-ray, CT and MRI findings of 26 cases with pathology proven PBL were retrospectively analyzed. Results: Of 26 cases, 14 cases were male and 12 cases were female with a mean age (40.7±5.8) years(range 20 to 73 years). The lesions of PBL were located in the skull(n=7), the femur(n=5), the humerus(n=4), the spine(n=4), the collarbone(n=2), the ilium(n=2), the tibia(n=1), fibula(n=1) in 26 cases. The X-ray and CT findings: dissolved bone type(n=21), hybrid type(n=3), sclerosis type(n=1), cystic type(n=1). Three cases were with the pathological fracture, 3 cases with the slight periosteal reflect, and 21 cases with apparent mass lesion(n=21). MRI findings(n=7): the uniform signal (n=3), the nonuniform signal (n=4); the lesions in isosignal or slightly low signal on T1WI, the slightly high signal on T2WI(n=5), the isosignal(n=2). The enhanced scanning(n=7): the moderate strengthening(n=5), the significantly strengthen(n=1), mild strengthen(n=1). Conclusion: PBL imaging has certain characteristics, the bone destruction often appear in dissolved bone type, give priority to with moderate enhancement, often accompanied by obvious soft tissue mass.
