Relationship of myocardial segmental mechanics and regional volume change with#br# left ventricular systolic synchrony in patients with coronary heart disease
1. Department of Cardiac Ultrasound, the Affiliated Hospital of Qingdao University, Qingdao Shandong 266003, China;
2. Department of Ultrasound, Shangdong Provincial Hospital Affiliated to Shangdong University, Jinan 250021, China
Abstract：Objective: To explore the relationship of myocardial segmental mechanics and regional volume change with left ventricular systolic asynchrony in patients with coronary heart disease(CHD) by real-time three-dimensional echocardiography(RT-3DE) and two-dimensional speckle imaging(2D-STI). Methods: Twenty-four patients with myocardial ischemia(myocardial ischemia group), 26 patients with myocardial infarction(myocardial infarction group) and 30 normal subjects(control group) were enrolled in this study. All patients were measured with 2D-STI and RT-3DE. Images were acquired and analyzed off-line on Qlab 8.1 station. The left ventricular myocardial segmental mechanics time indexes and standard deviation(Tls-16%, Trs-12%, Tcs-12%, Trot-12%, and Tls-16-SD%, Trs-12-SD%, Tcs-12-SD%, Trot-12-SD%), the left ventricular regional volume change time index and standard deviation(Tmsv-16% and Tmsv-16-SD%) were obtained, respectively. The difference between myocardial segmental mechanics and regional volume change(Tlsv%, Trsv%, Tcsv%, Trotv%) were calculated. Results: Compared with control group, Tls-16%, Tls-16-SD%, Tmsv-16%, Tmsv-16-SD% and Tlsv% were significantly prolonged(P<0.05) in myocardial ischemia group. Compared with myocardial ischemia group and control group, all the above time indexes had significant differences(P<0.05, P<0.01) in myocardial infarction group. Tlsv%, Trsv%, Tcsv% and Trotv% were significantly negatively correlated with LVEF, respectively in myocardial infarction group. Conclusion: Tlsv%, Trsv%, Tcsv% and Trotv% can become new indicators to assess the left ventricular asynchrony in myocardial infarction patients. Tlsv% is a potential sensitive indicator to evaluate the left ventricular asynchrony in myocardial ischemia patients.
张小花1，姜志荣1，宋家光2，张 楠2. 冠心病患者左心室心肌节段力学和局部容积负荷间关系与#br# 左室收缩同步性的研究[J]. 中国临床医学影像杂志, 2016, 27(7): 471-474.
ZHANG Xiao-hua1, JIANG Zhi-rong1, SONG Jia-guang2, ZHANG Nan2. Relationship of myocardial segmental mechanics and regional volume change with#br# left ventricular systolic synchrony in patients with coronary heart disease. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(7): 471-474.
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