Abstract:Objective: To compare the diagnostic efficiency of 18F-FDG coincidence SPECT/CT and 99mTc-MDP bone scintigraphy in the detection of bone metastasis of lung cancer. Methods: A total of 45 patients with lung cancer accepted both 18F-FDG coincidence SPECT/CT imaging and bone scintigraphy sequentially within 2 weeks were retrospectively studied. The differences of diagnostic efficiency on bone metastasis between the two examinations were analyzed. Bone metastases were confirmed by clinical follow-up for at least 6 months. Results: The sensitivity and specificity of 18F-FDG coincidence SPECT/CT for detecting bone metastases of lung cancer were 100% and 97%. The sensitivity and specificity of bone scintigraphy for detecting bone metastases of lung cancer were 92% and 66%. Significant statistical difference was found between 18F-FDG coincidence SPECT/CT imaging and bone scintigraphy for detecting bone metastasis of lung cancer(χ2=4.92, P<0.05). Conclusion: 18F-FDG coincidence SPECT/CT is superior to bone scintigraphy in detecting bone metastasis of lung cancer, meanwhile has the merit to find primary or metastatic tumor outside the bone. 18F-FDG coincidence SPECT/CT is valuable for clinical application.
方圣伟,韩苏阳,张佩佩,赵春雷. 18F-FDG符合线路SPECT/CT显像及99mTc-MDP骨显像对#br#
肺癌骨转移瘤诊断价值的对比研究[J]. 中国临床医学影像杂志, 2016, 27(9): 649-653.
FANG Sheng-wei, HAN Su-yang, ZHANG Pei-pei, ZHAO Chun-lei. Comparative study on diagnostic value of 18F-FDG coincidence SPECT/CT and 99mTc-MDP bone#br#
scintigraphy in bone metastasis of lung cancer. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(9): 649-653.