Abstract：Objective: To evaluate the value of ultrasonographic measurement of prehepatic fat thickness in the diagnosis of metabolic syndrome. Methods: Four hundred and ninety-six cases of community endocrinology follow-up were divided into groups according to metabolic syndrome. Ultrasound was used to measure the prehepatic fat thickness and the visceral fat thickness. The correlation between prehepatic fat thickness, intra-abdominal fat thickness and waist circumference was analyzed. ROC curve was used to analyze the optimal critical value of prehepatic fat thickness for the diagnosis of metabolic syndrome. Results: There was a positive correlation between the prehepatic fat thickness, the visceral fat thickness and the waist circumference(P<0.01). The correlation coefficient between the prehepatic fat thickness and waist circumference is more than that of the visceral fat thickness and waist circumference. The optimal critical value of the prehepatic fat thickness of male in diagnosing metabolic syndrome was 1.30 cm, the sensitivity and specificity was 0.70 and 0.81, the area under the curve was 0.82(P<0.01). The optimal critical value of the prehepatic fat thickness of female in diagnosing metabolic syndrome was 1.27 cm, the sensitivity and specificity was 0.88 and 0.74, the area under the curve was 0.87(P<0.01). Conclusion: Instead of the waist circumference, ultrasound measurement of prehepatic fat thickness is one of an accurate indicator metabolic syndrome of the degree of accumulation of intra-abdominal fat.
周冰冰，王学梅，张 茜，徐世燚，王浩宇. 超声测量肝前脂肪厚度对诊断代谢综合征的价值[J]. 中国临床医学影像杂志, 2017, 28(8): 560-563.
ZHOU Bing-bing, WANG Xue-mei, ZHANG Qian, XU Shi-yi, WANG Hao-yu. The value of ultrasonographic measurement of prehepatic fat thickness in the diagnosis of metabolic syndrome. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(8): 560-563.
[1]顾东风，Reynolds K，杨文杰，等. 中国成年人代谢综合征的患病率[J]. 中国糖尿病杂志，2005，13（3）：181-186.
[2]Cioffi G, Faggiano P, Lucci D, et al. Inappropriately high left ventricular mass in patients with type 2 diabetes mellitus and no overt cardiac disease. The DYDA study[J]. J Hypertens, 2011, 29(10): 1994-2003.
[3]Wolever TM, Mehling C. Long-term effect of varying the source or amount of dietary carbohydrate on postprandial plasma glucose, insulin, triacylglycerol, and free fatty acid concentrations in subjects with impaired glucose tolerance[J]. Am J Clin Nutr, 2003, 77(3): 612-621.
[4]杨虹，卢学勉，陈良苗，等. B超测量腹内脂肪厚度在代谢综合征诊断中的应用价值[J]. 中国全科医学，2008，11（18）：1635-1637.
[5]万里凯. 超声检测女性肝前脂肪厚度与内脏脂肪厚度的相关性研究[J]. 广西医学，2009，31（11）：1599-1600.
[6]Wajchenberg BL. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome[J]. Endocr Rev, 2000, 21(6): 697-738.
[7]郑洪来，周俊，冯征. 腹部脂肪分布与冠心病的相关性研究[J]. 中国医学影像学杂志，2003，11（3）：210-211.
[8]张力翔. 人体皮下脂肪和内脏脂肪在内分泌代谢方面的差异研究进展[J]. 医学综述，2013，19（14）：2511-2513.
[9]杨培胜，刘新红，黄淑华，等. 超声测量腹部肝前脂肪最大厚度预测冠状动脉疾病的发生及严重性[J]. 临床超声医学杂志，2013，15（3）：157-160.
[10]Fox CS, Massaro JM, Hoffmann U, et al. Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study[J]. Circulation, 2007, 116(1): 39-48.
[11]Gibby JT, Njeru DK, Cvetko ST, et al. Volumetric analysis of central body fat accurately predicts incidence of diabetes and hypertension in adults[J]. BMC Obes, 2015, 2: 10.
[12]Stolk RP, Wink O, Zelissen PM, et al. Validity and reproducibility of ultrasonography for the measurement of intra-abdominal adipose tissue[J]. Int J Obes Relat Metab Disord, 2001, 25(9): 1346-1351.
[13]Tadokoro N, Shinomiya M, Yoshinaga M, et al. Visceral fat accumulation in Japanese high school students and related atherosclerotic risk factors[J]. J Atheroscler Thromb, 2010, 17(6): 546-557.
