ADC值联合磁共振动态增强对前列腺癌伴发精囊腺侵犯的诊断价值

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摘要目的：探讨磁共振扩散加权成像（DWI）及表观扩散系数（ADC）值、3.0T MRI动态对比增强（DCE-MRI）对前列腺癌（Prostate cancer，PCa）伴发精囊腺侵犯（Seminal vesicle invasion，SVI）的诊断价值。方法：对50例PCa患者行DWI及DCE-MRI扫描，观察SVI的DWI及DCE-MRI表现，分别测量PCa癌灶、SVI以及正常精囊腺（Normal seminal vesicle，NSV）的ADC值并绘制出信号强度-时间（SI-T）曲线，计算出达峰时间（Tmax）、最大强化程度（SImax%）和最快强化率（Rmax），作统计学分析，并计算两种检查方法的敏感性、特异性及准确性。结果：本组PCa癌灶、SVI的DWI呈高信号影，ADC图呈低信号影。PCa癌灶、SVI、NSV的ADC值分别为（0.928±0.128）×10-3 mm2/s、（0.965±0.161）×10-3 mm2/s、（2.785±0.235）×10-3 mm2/s。SVI的ADC值明显低于NSV（t=20.896，P<0.05）， PCa癌灶与SVI的ADC值之间无明显统计学意义（t=2.013，P>0.05；F＝1.423，P>0.05）。PCa伴发SVI DCE-MRI表现为早期明显强化，SI-T曲线以速升缓降型和速升平台型多见，侵犯组和非侵犯组Tmax、SImax%、Rmax差异均有统计学意义（t＝－9.05、4.75、16.95，P＜0.05），DWI及DCE-MRI联合应用明显提高诊断的敏感性、特异性和准确性。结论：ADC值联合DCE-MRI有助于PCa伴发SVI的诊断。

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	王中娟
	吴文娟
	姜春娟
	汪桦

关键词 ：前列腺肿瘤, 磁共振成像

Abstract：Objective: To explore the diagnostic value of apparent diffusion coefficient(ADC) and magnetic resonance dynamic contrast-enhanced imaging(DCE-MRI) in prostate cancer(PCa) and seminal vesicle invasion(SVI). Methods: DWI and DCE-MRI data of 50 cases of pathologically proved PCa was retrospectively analyzed. DWI and ADC map appearance of all Pca foci, SVI and normal seminal vesicle(NSV) were analyzed. And their ADC mean values were measured. The styles of the SI-T were analyzed. Tmax, SImax%, Rmax were calculated. Sensitivity, specificity and accuracy were calculated also. Results: All PCa foci and SVI showed high signal intensity on DWI and low signal intensity on ADC map. The mean ADC values of PCa, SVI, NSV were (0.928±0.128)×10-3 mm2/s, (0.965±0.161)×10-3 mm2/s, (2.785±0.235)×10-3 mm2/s respectively. There was statistical significance among the SVI and NSV(t=20.896, P<0.05). There was no statistical significance among the PCa and SVI(t=2.013, P>0.05; F＝1.423, P>0.05). PCa and SVI in DCE-MRI showed early enhanced, the common styles of SI-T curves were rapidly ascending followed with descending curve. The value of Tmax, SImax%, Rmax in SVI and NSV were statistical significant(t＝-9.05, 4.75, 16.95, P＜0.05). DWI combined DCE-MRI can obviously increase the diagnostic sensitivity, specificity and accuracy. Conclusion: ADC combined with DCE-MRI might be helpful in diagnosis of PCa and SVI.

Key words： Prostatic neoplasms Magnetic resonance imaging

收稿日期: 2017-04-11

PACS:	Ｒ737.25
	Ｒ445.2

通讯作者: 王中娟，无锡市第二人民医院影像科，214002。E-mail：shelleywzj@126.com

作者简介: 王中娟（1984-），女，江苏盐城人，主治医师。E-mail：shelleywzj@126.com

引用本文:

王中娟，吴文娟，姜春娟，汪桦. ADC值联合磁共振动态增强对前列腺癌伴发精囊腺侵犯的诊断价值[J]. 中国临床医学影像杂志, 2018, 29(2): 102-104.
WANG Zhong-juan, WU Wen-juan, JIANG Chun-juan, WANG Hua. Prostatic neoplasms; Magnetic resonance imaging. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(2): 102-104.

链接本文:

http://www.jccmi.com.cn/CN/ 或 http://www.jccmi.com.cn/CN/Y2018/V29/I2/102

[1]Pierorazio PM, Ross AE, Schaeffer EM, et al. A contemporary analysis of outcomes of adenocarcinoma of the prostate with seminal vesicle invasion(pT3b) after radical prostatectomy[J]. J Urol, 2011, 185(5): 1691-1697.
[2]Wang L, Hricak H, Kattan MW, et al. Prediction of seminal vesicle invasion in prostate cancer: incremental value of adding endorectal MR imaging to the Kattan nomogram[J]. Radiology, 2007, 242(1): 182-188.
[3]Rothke M, Blondin D, Schlemmer HP, et al. PI-RADS classification: Structured reporting for MRI of the prostate(in German)[J]. Rofo, 2013, 185(3): 253-261.
[4]Hoeks CM, Barentsz JO, Hambrock T, et al. Prostate cancer: multiparametric MR imaging for detection, localization, and staging[J]. Radiology, 2011, 261(1): 46-66.
[5]Rouse P, Shaw G, Ahmed HU, et al. Multi-parametric magnetic resonance imaging to rule-in and rule-out clinically important prostate cancer in men at risk: a cohort study[J]. Urol Int, 2011, 87(1): 49-53.
[6]De Visschere PJ, Briganti A, Fütterer JJ, et al. Role of multiparametric magnetic resonance imaging in early detection of prostate cancer[J]. Insights Imaging, 2016, 7(2): 205-214.
[7]Roethke M, Kaufmann S, Kniess M, et al. Seminal Vesicle Invasion: Accuracy and Analysis of Infiltration Patterns with High-Spatial Resolution T2-Weighted Sequences on Endorectal Magnetic Resonance Imaging[J]. Urol Int, 2014, 92(3): 294-299.
[8]Jing R, Yi H, He W, et al. Seminal vesicle invasion in prostate cancer: prediction with combined T2-weighted and diffusion-weighted MR imaging[J]. Eur Radiol, 2009, 19(10): 2481-2486.
[9]Soylu FN, Peng Y, Jiang Y, et al. Seminal vesicle invasion in prostate cancer: evaluation by using multiparametric endorectal MR imaging[J]. Radiology, 2013, 267(3): 797-806.
[10]Couago F, Del Cerro E, Díaz-Gavela AA, et al. Tumor staging using 3.0T multiparametric MRI in prostate cancer: impact on treatment decisions for radical radiotherapy[J]. Springerplus, 2015, 18(4): 789-794.
[11]Turkbey B, Brown AM, Sankineni S, et al. Multiparametric prostate magnetic resonance imaging in the evaluation of prostate cancer[J]. CA Cancer J Clin, 2016, 66(4): 326-336.