Abstract：Objective: To investigate the clinical values and manifestations of early joint lesion in patients with hemophilia by using the ultrasonographic. Methods: Forty-seven patients were diagnosed with moderate to severe hemophilia on the knee, elbow and ankle joints on color Doppler ultrasonography image. The joint ultrasound characteristics were scored with HEAD-US scoring system and graded according to level of the synoval blood flow. Results: Synovial hyperplasia was found in 21.7%(60/277) of the joints, cartilage destruction was showed in 9.4%(26/277) of the joints and bone destruction was displayed in 10.1%(28/277) of the joints. The correlation between HEAD-US score, synovial hyperplasia, synovial blood flow and the number of bleedings within half year and total number of bleeding is positive. Conclusion: Ultrasound can find many early joint lesions in hemophilia patient, it is hopeful to be a feasible and reliable tool to evaluate the early joint disease of hemophilia and guide individual treatment.
高树熹，李建民，王 欢. 彩色多普勒超声评价血友病患者早期关节病变的应用价值[J]. 中国临床医学影像杂志, 2018, 29(2): 126-129.
GAO Shu-xi, LI Jian-min, WANG Huan. Application value of color Doppler ultrasonography examination on early joint lesion in hemophilia patients. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(2): 126-129.
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