Abstract:Objective: To observe the short-term and long-term effects of ultrasound-guided microwave ablation(MWA) in the treatment of benign thyroid nodules(BTN) and its effects on thyroid stimulating hormone(TSH), free triiodothyronine(FT3) and free thyroxine(FT4) level of influence. Methods: Ninety-five patients with BTN were divided into the conventional group(46 cases, conventional thyroidectomy) and the observation group(49 cases, ultrasound-guided MWA treatment) depending on the treatment. The perioperative parameters of the two groups were compared. The curative effect at 1, 3, 6, 12, 18 months postoperatively of observation group was observed. The levels of TSH, FT3, and FT4 before operation and 6 months after operation were compared of the two groups. The complications were statisticed and compared between the two groups. Results: The operation time and hospitalization time of the observation group were shorter than those of the conventional group(P<0.05), which of the intraoperative blood loss was less than that of the conventional group(P<0.05), which of the postoperative scar length was shorter than the conventional group(P<0.05). After the prolongation of time, the volume of nodules in the observation group showed a significant decrease(P<0.05), and the rate of nodule reduction showed a significant increase(P<0.05). The level of TSH in the conventional group increased 6 months after operation(P<0.05), which of the levels of FT3 and FT4 were reduced(P<0.05). The TSH level of the observation group was lower than that of the conventional group(P<0.05), which of the FT3 and FT4 levels were higher than those of the conventional group(P<0.05). The total complication rate of the observation group was lower than that of the conventional group(P<0.05). Conclusion: Ultrasound-guided MWA is effective in the treatment of BTN in short-term and long-term. Compared with conventional thyroidectomy, its operation time is shorter, intraoperative blood loss is less, scar is shorter, the recovery speed is faster, the thyroid function is less affected, and the complications are less.
石太英,尚缜邈,张琪茹. 超声引导下微波消融对甲状腺良性结节的近远期疗效及对TSH、FT3、FT4水平的影响[J]. 中国临床医学影像杂志, 2020, 31(6): 390-393.
SHI Tai-ying, SHANG Zhen-miao, ZHANG Qi-ru. Short-term and long-term effects of ultrasound-guided microwave ablation on benign thyroid nodules and its effects on TSH, FT3 and FT4 levels. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(6): 390-393.