58例超级骨显像分析

doi:10.12117/jccmi.2020.06.017

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摘要目的：探讨超级骨显像的病因、影像学特点，以及不同病因组患者年龄、碱性磷酸酶（ALP）、血钙水平之间的差异。方法：回顾性分析58例超级骨显像病例的临床资料，根据病因不同，将恶性肿瘤骨转移患者分为转移组，代谢性骨病患者分为代谢组，统计分析两组患者年龄、ALP、血钙水平差异；并依据超级骨显像图像特点不同分为均匀对称性（Ⅰ型）和灶性散在分布型（Ⅱ型）2种类型进行分析。结果：超级骨显像的阳性率为0.32%（58/18 406），其中骨转移最常见，其次为代谢性骨病。均一对称型影像占58.6％（34/58），骨转移患者占Ⅰ型影像的44.8％（26/58），代谢性骨病患者占Ⅰ型影像的13.8％（8/58）。转移组患者平均年龄大于代谢组，ALP水平高于代谢组，而血钙水平代谢组高于转移组，差异有统计学意义（P均<0.05）。结论：超级骨显像病因以骨转移最为常见，骨转移及代谢性骨病均可表现为均匀对称性的超级骨显像特点，年龄、ALP、血钙对鉴别两种病因的超级骨显像有一定的价值。

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	曾令鹏1
	罗侃莹2
	张庆1
	张青1

关键词 ：骨肿瘤, 骨疾病, 放射性核素显像

Abstract：Objective: To investigate the etiology, imaging characteristics of super bone imaging, and the differences in age, alkaline phosphatase(ALP), and serum calcium levels among patients with different etiology. Methods: The clinical data of 58 cases with super bone imaging were retrospectively analyzed. According to different causes, patients with malignant bone metastases were divided as metastasis group, and metabolic bone disease patients were divided as metabolome group, then the differences in age, ALP and serum calcium levels between the two groups were statistically analyzed. According to the characteristics of super bone imaging images, it was divided into two types: uniform symmetry(type Ⅰ) and focal scattered distribution type(type Ⅱ). Results: The positive rate of super bone imaging was 0.32%(58/18 406), of which bone metastases were the most common, followed by metabolic bone disease. Uniform symmetrical images accounted for 58.6%(34/58), and bone metastases and metabolic bone disease accounted for 44.8%(26/58) and 13.8%(8/58) among those patients. The average age and the ALP level of the patients in the metastatic group were higher than that in the metabolome group, while the blood calcium level of patients in the metabolome group was higher than that in the metastatic group, the difference was statistically significant(P<0.05). Conclusion: Bone metastases are the most common causes of super bone imaging. Both bone metastasis and metabolic bone disease can be characterized by super bone imaging with uniform symmetry. Age, ALP and serum calcium are valuable in the identification of the two etiologies of super bone imaging.

Key words： Bone neoplasms Bone diseases Radionuclide imaging

收稿日期: 2019-10-24

PACS:	Ｒ738.1
	Ｒ681
	Ｒ817.4

通讯作者: 张青，南昌大学第一附属医院核医学科，330006。E-mail：zlphyx@163.com

作者简介: 曾令鹏（1989-），男，江西吉安人，住院医师。E-mail：863138869@qq.com

引用本文:

曾令鹏1，罗侃莹2，张庆1，张青1. 58例超级骨显像分析[J]. 中国临床医学影像杂志, 2020, 31(6): 446-449.
ZENG Ling-peng1, LUO Kan-ying2, ZHANG Qing1, ZHANG Qing1. Analysis of super bone imaging in 58 cases. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(6): 446-449.

链接本文:

http://www.jccmi.com.cn/CN/10.12117/jccmi.2020.06.017 或 http://www.jccmi.com.cn/CN/Y2020/V31/I6/446

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