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| Value of echocardiographic indices in predicting the spontaneous closure of ductus arteriosus among neonates |
| ZENG Hui-ru1, ZHAO Jin-hui2, LIU Tong1, LI Ling1 |
| 1. Department of Special Diagnosis, No.202 Hospital of PLA, Shenyang 110003, China;2. Ultrasonic Department, the Affiliated Hospital of Hebei University, Baoding Hebei 071000, China |
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Abstract Objective: To investigate whether the spontaneous closure of ductus arteriosus could be predicted by early echocardiographic indices. Methods: The term neonates were examined with echocardiography 1 to 3 days after birth. The presence or absence of a hemodynamically significant ductus shunt was judged from echocardiographic indices. If the ductus arteriosus was not closed, follow-up research were made. From January 1995 to March 2005, there were 45 subjects in our hospital whose ductus did not close spontaneously within a one-year follow-up(PDA group), and 50 subjects whose ductus closed spontaneously within 3 days were collected randomly served as controls(CONTROL group). The echocardiographic indices were compared between the two groups. Results: The LA/AO, LVIDd/AO, the smallest width of ductal color Doppler flow jet and the velocity at the pulmonary end of the duct in PDA group were found to be significantly higher than those in CONTROL group(P<0.001, P<0.01, P<0.001, P<0.001 respectively). LA/AO<1.30, LVIDd/AO<1.82, and the smallest width of ductal color Doppler flow jet<0.29cm were good indicators for prediction that the ductus arteriosus could be closed spontaneously. LA/AO>1.39, LVIDd/AO>1.97, and the smallest width of ductal color Doppler flow jet>0.33cm indicated that the ductus arteriosus could not be closed spontaneously, and further treatment was necessary. Conclusion: The early echocardiographic indices of term neonates was very valuable to predict the spontaneous closure of ductus arteriosus.
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Received: 24 June 2005
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2006, Vol. 17 
