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A comparative study on mean flow density of hepatic tumor before and after enhanced ultrasonography |
ZHANG Feng-juan, ZHAO Yu-zhen, MENG Jie, JI Xiao-hui, YANG Yi |
Department of Ultrasound, the Fourth Hospital, Hebei Medical University, Shijiazhuang 050011, China |
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Abstract Objective: To explore the clinical application of quantitative index-MFD(mean flow density) before and after contrast-enhanced ultrasound(CEUS) in evaluating the blood supply of hepatic tumor. Methods: Thirty-five hepatic solid lesions, 11 cases of hepatocellular carcinomas(HCC), 9 cases of metastatic liver tumors(MLT), 15 cases of hepatic hemangiomas(HCH), were examined with color power angiography(CPA) before enhanced ultrasonography, then they were examined with pulse-inversion harmonic(PIH) ultrasonographic imaging after an intravenous administration of SonoVue. MFD were calculated and analysed before and after enhanced ultrasonography respectively. Results: There were significant difference of MFD before and after enhanced ultrasonography in each group(P<0.05). The MFD of HCC(0.303±0.179) were obviously higher than HCH(0.093±0.064) in enhanced ultrasonography(P<0.05). There was no obvious difference between MLT and the other two groups separately. Conclusion: can provide an important information for differential diagnosis between HCC and HCH after CEUS.
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Received: 15 August 2005
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