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| An application study of magnetization transfer imaging in differentiating brain abscess from necrotic or cystic neoplasm |
| YAO Xiu-zhong, CHEN Shi-yong, LAI Qing-quan, NIAN Chao-hui, WU Hong, LU Wen-qian |
| Department of Radiology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou Fujian 362000, China |
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Abstract Objective: To study the value of magnetization transfer imaging(MTI) in the differentiation of brain abscess from necrotic or cystic glioma and metastasis. Materials and Methods: The conventional MR imaging and MTI of SE sequence were performed before operation or treatment in 7 patients with brain abscess(3 cases histopathology verified and 4 cases clinical follow-up confirmed) and 9 patients with necrotic or cystic glioma(confirmed by histopathology) and 8 patients with necrotic or cystic metastasis (clinically confirmed). Mean MTR of cystic and solid parts in abscess, glioma and metastasis, contralateral normal white matters and cerebrospinal fluid were measured and calculated. Results: MTR of cystic and solid parts in all lesions, contralateral normal white matter and cerebrospinal fluid were 0.0770±0.03, 0.2239±0.03, 0.3089±0.020, -0.0032±0.03 respectively. The difference of MTR between cystic parts of all lesions and cerebrospinal fluid was significant(t=9.933, P<0.001). The difference of MTR between solid parts of all lesions and contralateral normal white matters was significant(t=-14.509, P<0.001). The difference of MTRs among abscess, necrotic or cystic area of glioma and metastasis was significant(χ2=17.486, P<0.001), especially, there was significant difference between abscess and necrotic or cystic area of glioma or metastasis(abscess&glioma: P<0.001 and abscess&metastasis: P<0.001), however, there was no difference between necrotic or cystic area of glioma and metastasis(P>0.20). The difference of MTR among solid parts of abscess, glioma and metastasis was not significant. Conclusion: MT imaging and MTR could play an important role in differentiating brain abscess from necrotic or cystic glioma and metastasis on the middle feild, and MR system was an important supplement for routine MRI.
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Received: 04 February 2006
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2006, Vol. 17 
