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| Diagnostic value of dynamic enhanced MRI and MRCP in cholangiocarcinoma caused by clonorchiasis |
| LI Li, LI Jian-zhang, XIANG Zhi-ming, GUANG Xue-ting, ZHANG Ping-ping |
| Department of Radiology, Panyu Central Hospital, Guangzhou 511400, China |
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Abstract Objective: To explore diagnostic value of dynamic enhanced MRI and MR cholangiopancreatography(MRCP) in cholangiocarcinoma caused by clonorchiasis and its possible pathogenesis. Methods: 28 patients with cholangiocarcinoma caused by clonorchiasis who were confirmed by surgery or pathology were enrolled in the study. Their MRI and MRCP features were retrospectively analyzed including the location, size, shape, signal intensity and enhancement pattern of the tumors, and the characteristics of bile duct dilatation. Results: There were 9 cases in mass-type, 16 cases in infiltrative-type and 3 cases in intracavitary-type. The MRI features of most tumors were hypointense on T1WI and inhomogeneouly hyperintense on T2WI. Tumors of mass-type and infiltrative-type showed gradual centripetal contrast enhancement. Tumors of intracavitary-type showed homogeneously enhanced filling defects in the bile ducts. On MRCP, the mass-type showed slight to moderate dilatation of intrahepatic biliary ducts around the tumors, with diffuse saccular dilatation of terminal intrahepatic bile ducts. The infiltrative-type and intracavitary-type showed moderate to severe dilatation of the biliary ducts. Conclusion: Clonorchiasis is an important cause for cholangiocarcinoma. The feature of clonorchiasis is saccular dilation of terminal intrahepatic bile ducts. Dynamic enhanced MRI with MRCP is an important technique for accurate diagnosis of cholangiocarcinomas caused by clonorchiasis.
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Received: 25 June 2014
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2015, Vol. 26 
