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| Diagnostic value of contrast-enhanced ultrasound in the diagnosis of breast benign and malignant lesions |
| CHEN Jun, YAN Ping, ZHANG Bo, WU Tao |
| Department of Ultrasound, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China |
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Abstract Objective: To evaluate the diagnostic value of contrast-enhanced ultrasound in the diagnosis of breast lesions. Methods: Sixty-two cases of breast lesions, in which 33 cases were benign, and 29 were malignant, were examined with contrast-enhanced ultrasound. The enhancement pattern, time-intensity curve and contrast parameters were analyzed to compare the differences between benign and malignant lesions. Results: Significant differences were found in homogeneity of the intensity, the initial enhancement time, peak time and the slope rate(all P<0.05). No significant difference were found in peak intensity, average intensity and areas under peak～60s of the time-intensity curves. The inhomogenity of the intensity, the time from initial enhancement<10s, peak time <20s and the slope rate<5 were set as the indicators for malignancy. The diagnostic accuracy of B-ultrasound and color Doppler flow imaging is 88.7%, when combined with contrast-enhanced ultrasound, the diagnostic value can be improved to 93.6%. Conclusions: Contrast-enhanced ultrasound can improve the accuracy of diagnosis for breast lesions.
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Received: 18 June 2008
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2009, Vol. 20 
