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| Imaging findings of chondromyxoid fibroma of bone |
| ZHOU Jian-jun, WANG Jian-hua, ZENG Meng-su, YAN Fu-hua, ZHOU Kang-rong, DING Jian-guo, JI Yuan |
| Zhongshan Hospital, Fudan University, Shanghai 200032, China |
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Abstract Objective: To explore the imaging features of chondromyxoid fibroma of bone and evaluate their clinical value. Methods: Eleven cases with chondromyxoid fibroma of bone confirmed by surgical pathology underwent radiography, CT plain scanning and MR SE-T1WI, SE-T2WI and SE-T1WI enhanced scanning before operation, the imaging data was reviewed and analysed retrospectively in comparison with surgical and pathological results. Results: The lesions in seven cases of 11 chondromyxoid fibroma with well defined osteolytic destruction were located at the metaphysis of the long tubular bone, in 2 cases the lesion was in pelvis, 1 case in skull, the other case in vertebrae. The diameter of the tumor ranged from 3.2cm to 16.9cm, with a mean diameter of 4.7cm. When located in a long tubular bone, chondromyxoid fibroma were generally eccentrically situated at the metaphysis, radiolucent and elongated in shape, cortical expansion, exuberant endosteal sclerosis, and coarse trabeculation, with small area of ring- and arc-like calcification, thin sclerotic rim separated the tumor from adjacent normal bone, there may be little periosteal reaction and small soft tissue masses. The CT value was similar to muscle and CT is optimal to detect the matrix mineralization. MR imaging depicted low signal intensity with well defined rim on T1WI, high signal intensity on T2WI. Conclusion: The imaging manifestations of chondromyxoid fibroma were specific to some extent. Combined utilization of plain X-ray, CT, and MRI is helpful for the diagnosis and differential diagnosis of chondromyxoid fibroma.
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Received: 11 August 2008
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2009, Vol. 20 
