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| Experimental study of preoperative volume evaluation in living donor liver transplantation using 64-slice spiral CT |
| ZHOU Xing1, ZHOU Huai-qi1, GUO Ji-gang1, CAO Xiao-feng2, CHEN Ying-tai1, XU Feng1 |
| 1. The First Hospital of Lanzhou University, Lanzhou 730000, China;2. Department of Urology, the Second Hospital of Lanzhou University, Lanzhou 730000, China |
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Abstract Objective: To study the accuracy of liver volume measurement using 64-slice spiral CT(64-SCT) and analyze sources of such inaccuracies with regard to CT liver volume and actual liver volume through simulating donor liver resected with perfusion of liver transplantation, and analyze relationship of actual liver volume and the weight of the liver. Methods: Thirty rabbits were randomly assigned as experiment group and control group(15 for each); thirty rabbit livers were scanned using 64-SCT at three enhancement phases. The imaging data with two axial 2-D CT slices (1mm and 3mm) at the hepatic venous phase and portal venous phase was used for whole liver volumetry or measured on a dedicated image post-processing work station; Each actual liver volume and their weight were measured by water displacement and scales immediately, experiment group were simulated donor liver perfusion of liver transplantation, control group liver blood vessel were ligated prior to resection respectively. Results: The difference of CT liver volume and actual liver volume in the two groups were 20.2%±0.5%, 6.29%±0.43%, respectively. Liver density was (1.000±0.011)g/ml, (1.003±0.007)g/ml respectively. The CT liver volume were positively of the two groups correlated with actual liver volume(r=0.981, r=0.979, r=0.977, r=0.985, r=0.992, r=0.988, r=0.982, r=0.987, P<0.001), ANOVA indicated liver resected with perfusion of liver transplantation was the main sources of such inaccuracies with regard to CT liver volume and actual liver volume (F=420.380, P<0.05). No significant difference between the difference of CT liver volume in two slices and two phases(P>0.05, P>0.05), independent-sample t-test indicated liver density of two groups has no significant difference(t=-1.076, P>0.05). Conclusion: The positive correlation between CT liver volume and actual liver volume, the main sources of such difference between CT liver volume and actual liver volume was liver resected with perfusion of liver transplantation. 64-SCT can assess the liver volume correctly and can be repeatedly.
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Received: 30 September 2008
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Corresponding Authors:
ZHOU Huai-qi
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2009, Vol. 20 
