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Effect of transcatheter uterine arterial chemoembolization on VEGF, MVD of cervical carcinoma |
ZHANG Guo-ling, ZHAO Xin-jian, GAO Yong-chang |
Department of Radiology, the First Affiliated Hospital of Shihezi University, Shihezi Xinjiang 832002, China |
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Abstract Objective: To evaluate the influence of transcatheter uterine arterial chemoembolization on expression of vascular endothelial growth factor(VEGF) and micro vascular density(MVD) of cervical cancer. Methods: Immunohistochemical exam was performed to detect the expression of VEGF and MVD in 42 cases of cervical carcinoma before and after transcatheter uterine arterial chemoembolization. Results: After transcatheter uterine arterial chemoembolization, the expression of VEGF decreased from 67%(28/42) to 35%(15/42), while MVD also decreased remarkably(P<0.05). Conclusions: Transcatheter uterine arterial chemoembolization can decrease expression of VEGF and MVD and may able to suppress the growth and metastasis of cervical cancer.
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Received: 25 February 2008
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Corresponding Authors:
ZHAO Xin-jian
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