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| Measurement of fetal corpus callosum with three-dimensional ultrasound |
| ZHAO Dan1, CAI Ai-lu1, LIU Wei2, XIN Zhong-qiu3, YANG Ze-yu1, YANG Shu1, LI Ting1 |
| 1. Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, China; 2. Department of Ultrasound, Fushun Mineral Hospital, Fushun Liaoning 113008, China;3. Department of Ultrasound, Daqing Oilfield General Hospital, Daqing Heilongjiang 163001, China |
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Abstract Objective: To establish reference ranges for normal live fetal corpus callosum volume. Methods: A total of 160 pregnant women with normal live pregnancy between 21 to 36 weeks gestation were recruited into the study. The 3D volumes of the fetal brain were acquired for later volume calculation using the VOCAL application. Results: Measurements of the fetal corpus callosum for volume calculations were obtained in 160 women. There is a significant linear association between the volume of the corpus callosum and gestational age(r＝0.956, P<0.001). Conclusion: The fetal corpus callosum volume may be the sensitive parameter to evaluate the fetal CNS development with the establishing of normal fetal corpus callosum volume. And it can also be used for diagnosis of the fetuses suspected of agenesis of corpus callosum.
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Received: 28 February 2009
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2009, Vol. 20 
