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| Comparative study of SPECT between patients with depressive disorder and anxiety disorders |
| JIN Yu-xin, GAO De-jiu, LIU Lin |
| Department of Nuclear Medicine, the First People’s Hospital of Baiyin, Baiyin Gansu 730900, China |
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Abstract Objective: To study the characteristics of regional cerebral blood flow(rCBF) and the diagnostic value of brain SPECT in patients with depressive disorder and anxiety disorders. Methods: SPECT were performed in 21 depressive patients, 17 anxiety patients to compare the difference in cerebral perfusion. Region of interest(ROI) in cross-sectional images of the brain lobes were drawn, to semi-quantitatively analyse the rCBF changes of depression and anxiety disorders in patients. The t test was used to analyze the quantitative data. Results: Lower radioactivity rate in bilateral prefrontal lobes, temporal lobes, occipital lobes, bilateral parietal lobes, cingulated gyrus, caudate nucleus were demonstrated in the depressive patients(P＜0.05 or 0.01). Lower radioactivity rate in bilateral frontal lobes, anterior temporal lobes and cerebral ganglion were demonstrated in the anxiety patients(P＜0.05 or 0.01). Conclusion: The depressive disorder and anxiety disorders have obvious effect on cerebral blood flow. Radionuclide imaging have important value in the diagnosis and differential diagnosis of depressive disorder and anxiety disorders.
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Received: 01 January 1900
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2009, Vol. 20 
