1.Department of Ultrasound, Pudong New Area People’s Hospital, Shanghai 201200, China;2.Department of Ultrasound, Changzheng Hospital Second Military Medical University, Shanghai 200003, China
Abstract Objective: To evaluate the diagnostic value of three-dimensional ultrasonography in single thyroid nodule. Methods: 128 patients with single thyroid nodule were examined with three-dimensional ultrasonography to assess the characters of gray-scale and blood vessel morphology and distribution of thyroid nodules in three-dimensional ultrasonography. The results were compared with post-operative pathological results. The diagnostic value of three-dimensional ultrasonography was evaluated using receiver operating characteristic(ROC) curve. Results: Three-dimensional ultrasonography showed significant difference in the characters of gray-scale; vascular morphology and distribution of inner and surrounding vessels in malignant thyroid nodules in comparison to benign lessions(P<0.01). Using characteristics of three-dimensional gray-scale ultrasound as criteria of malignant and benign thyroid nodules, the area under ROC curve was 0.9218, diagnostic performances was better. Using surrounding blood vessels of thyroid nodules as criteria, the area under ROC curve was 0.8131, diagnostic performances was moderate. Using the whole character of gray-scale and blood vessel morphology and distribution in three-dimensional ultrasound as criteria, the area under ROC curve was 0.9608, diagnostic performance was the best. Conclusions: Three-dimensional ultrasound imaging can evaluate the characters of gray-scale and blood vessel morphology and distribution of thyroid nodules, and improve the capability in differentiating between malignant and benign thyroid nodules.
ZHANG Yuan,JIANG Quan,CHEN Jian, et al. The diagnostic value of three-dimensional ultrasonography in single thyroid nodule and the analysis of ROC curve[J]. , 2010, 21(1): 13-16.
2010, Vol. 21 
