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| Speckle tracking imaging in early assessment of thoracic radiotherapy-induced left ventricular systolic function damage at short-axial view |
| WANG Na1, YUAN Jian-jun2, TIAN Qing2 |
| (1. Department of Ultrasound, the Affiliated Hospital of Zhengzhou University, Zhengzhou 450003, China; 2. Department of Ultrasound, Henan Provincial People’s Hospital, Zhengzhou 450003, China) |
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Abstract Objective: To evaluate the value of speckle tracking imaging(STI) in detecting early thoracic radiotherapy-induced myocardial damage by using STI to quantitatively analyse the left ventricular systolic function at short-axial view. Methods: STI was performed in 46 patients with thoracic radiotherapy. The 46 patients were divided into three groups: group A: before radiation treatment(control group); group B: radiotherapy time was 2.5～3 weeks, radiotherapy dose was 26～30Gy; group C: radiotherapy time was 5～6 weeks, radiotherapy dose was 50～60Gy. Radial strain(RS) and circumferential strain(CS) were measured in the left ventricular short-axial view at the levels of mitral annulus and papillary muscle． Results: ①RS and CS of group C in anterior wall, anterior septal and posterior wall were significantly lower than those in group A(P<0.01); RS and CS of group C in anterior wall, anterior septal and posterior wall were lower than those in group B(P<0.05); RS and CS of group B in anterior wall, anterior septal and posterior wall compared with those in group A, had no significant difference(P>0.05); ②RS and CS of left lateral wall, posterior septal and inferior wall in all groups had no significant difference(P>0.05). Conclusions: RS and CS after the thoracic radiation treatment were significantly lower than those in the patients before radiation treatment, STI can indicate the change of heart disease in systolic function. STI is valuable to assess early thoracic radiotherapy-induced myocardial damage.
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Received: 21 February 2011
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Corresponding Authors:
YUAN Jian-jun
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2011, Vol. 22 
