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| Experience of 320-slice whole brain dynamic volume CT and perfusion imaging in patients with moyamoya disease |
| PAN Yu-ning, HUANG Qiu-li, YE Xian-wang, ZHANG Jie, LIAN Yan-dong, FU Fen-fen |
| Department of Radiology, Ningbo First Hospital, Ningbo Zhengjiang 315010, China |
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Abstract Objective: To evaluate the value of 320-slice whole brain dynamic volume CT angiography and CT perfusion imaging in moyamoya disease. Methods: Eighteen cases with moyamoya disease were examined with 320-slice whole brain dynamic volume CT. Imaging data were generated with volume rendering reconstruction and display in cine mode, and complete CT perfusion imaging were performed simultaneously. Results: We succeeded in obtaining plain images of whole-brain, dynamic CTA and whole-brain perfusion images in 18 patients, all of which showed lesions of stenosis and obstruction in internal carotid artery (ICA), proximum of Willis circle and posterior and middle cerebral arteries; abnormal vessel network in the basal part of brain; and the condition of collateral circulation in the brain. Perfusion weighted imaging revealed mean transit time(MTT) was extended(0.5~13s). Ten cases showed decrease in regional cerebral blood flow(rCBF), the amplitude was 26.0%~54.5%. There were 8 cases of normal and 4 cases decreased in regional cerebral blood volume(rCBV). Conclusion: Whole brain dynamic volume imaging with 320-detector row CT can provide 3D structure of vessels of the whole brain, and serial of the dynamic blood flow and cerebral perfusion in a single scanning, which has the potential diagnostic value in moyamoya disease.
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Received: 13 April 2011
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2011, Vol. 22 
