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| Differentiating segmental autoimmune pancreatitis from pancreatic carcinoma and pancreatic endocrine tumors on the basis of enhancement characteristics at dual-phase CT |
| NI Rui-jun1, WANG Bo-yin1, XU Shun-liang2, RUAN Ling-xiang2 |
| 1. Department of Radiology, Shaoxing People’s Hospital, Shaoxing Zhejiang 312000, China;2. The First Hospital of Zhejiang University Medical College, Hangzhou 310003, China |
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Abstract Objective: The purposes of this study was to investigate the difference of segmental autoimmune pancreatitis(AIP) from pancreatic carcinoma and pancreatic endocrine tumors(PECT) at dual-phase CT, and to improve the level of diagnosing AIP. Methods: Dual-phase CT scans of 75 patients(9 with segmental autoimmune pancreatitis, 25 with pancreatic carcinoma, 16 with pancreatic endocrine tumors, and 25 with a normal pancreas) were analyzed. Analyze the image findings including the uniformity of density, the shape of lesion, and the contrast density of masses to normal pancreatic parenchyma. The CT attenuation value of the pancreatic parenchyma and pancreatic masses were measured on plain scanning and on arterial- and portal venous phases. Compare the mean CT attenuation value of AIP to pancreatic carcinoma and PECT respectively, all of which were compared with normal pancreas. Results: In the arterial phase, all AIP manifested as hypodense to uninvolved pancreas, and all pancreatic carcinoma manifesed significantly hypodense to normal pancreas, and all PECT manifested hyperdense to normal pancreas; the mean CT attenuation values of AIP, pancreatic carcinoma, PECT and control group were 72.7HU, 49.2HU, 115.6HU and 93.4HU respectively. In the portal venous phase, all AIP manifested slightly hyperdense to uninvolved pancreas, and all pancreatic carcinoma manifesed significantly hypodense to normal pancreas, and all PECT manifested hyperdense to normal pancreas; the mean CT attenuation values of AIP, pancreatic carcinoma, PECT and control group were 86.6HU, 57.6HU, 104.2HU and 83.9HU respectively. Conclusion: At dual-phase CT, the enhancement patterns of AIP was different from that of the pancreatic carcinoma, the pancreatic endocrine tumor and normal pancreas. Dual-phase CT scanning played an important role in differentiating AIP from pancreatic carcinoma and pancreatic endocrine tumors.
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Received: 25 March 2011
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2011, Vol. 22 
