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Quantitative estimation of the relationship between foramen ovale-related parameters and the hypoplastic of left heart using fetal echocardiography |
FAN Zhi-na1, ZHAO Bo-wen2, YUAN Jian-jun1 |
1. Department of Ultrasonography, Henan People’s Hospital, Zhengzhou 450003, China;2. Department of Ultrasonography, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China |
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Abstract Objective: To investigate the clinical significance of foramen ovale-related parameters examined by echocardiography in the prenatal diagnosis of hypoplastic left heart. Methods: One hundred and eighty-eight cases of fetal foramen ovale-related parameters were obtained, to analyze its change with the gestational age, and study the relationship between foramen ovale-related parameters and fetuses with hypoplastic left heart. Results: In the 188 cases, 165 cases were nomal and 23 cases were abmomal associated with hypoplastic left heart(12 cases were hypoplastic left heart syndrome, 8 cases were aortic valve aortic stenosis, 3 cases were coarctation of aorta). Normal fetal foramen ovale valve flap diameter was similar to the aortic diameter, and normal fetuses had a smaller ratio of foramen ovale valve flap diameter/aortic root size than fetuses with hypoplastic left heart(P<0.01), but had a larger ratio of foramen ovale valve flap diameter/atrial septum size(P<0.01). Conclusion: The foramen ovale-related parameters examined by echocardiography has important significance in prenatal diagnosis of hypoplastic left heart.
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Received: 31 March 2011
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