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| Imaging features and clinical pathological analysis of pleuropulmonary blastoma in children |
| HU Yue-lin, LIU Hong-sheng, GAO Qiu, HUANG Li, LU Lian-wei, XIAO Wei-qiang, ZHOU Ning |
| Guangzhou Women and Children’s Medical Centre, Guangzhou 510623, China |
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Abstract Objective: To explore the images and clinical pathologic features of pleuropulmonary blastoma(PPB) and to improve the understanding of this disease. Methods: The imaging findings of 12 cases of PPB confirmed by pathology were analyzed retrospectively. They were divided into the Ⅰ, Ⅱ, Ⅲ types according to Dehuer calssfication. According to X-ray and CT examination in PPB of different types, the images and pathological features were analyzed. Results: A large mass of PPB was shown on X-ray image in thoracic cavity, which could oppress lung and mediastinal. A huge heterogeneous density mass beneath the pleura lung periphery was shown on CT image, often associated with pleural effusion, atelectasis. In post-contrasted enhancement image, the solid component showed obvious enhancement, while the cystic component showed no enhancement. Primitive embryonal round or oval cells were mainly composed of the tumor by microscopic examination. Vimentin and Desmin were shown positive in the immunohistochemical study. Conclusion: The diagnosis of PPB should be based on both the pathological and immunohistochemical evidences duing to lacking of photography features.
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Received: 22 December 2014
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2015, Vol. 26 
