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MRI diagnosis of cerebral complications in chemotherapy and transplantation of malignant hematopoiesis |
HOU Xue-wen, YU Hai-tao, ZHU An-hui, ZHANG Xiao-jin |
Department of Radiology, the Center Hospital of Aerospace, Beijing 100039, China |
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Abstract Objective: To study the MRI features of cerebral complications in treatment of malignant hematological diseases. Methods: Thirty cases of malignant hematological diseases without invasion of central nervous system, including 25 cases of leukemia, 4 cases of lymphoma, a case of multiple myeloma, confirmed by bone marrow biopsy were enrolled in the study. We studied the changes of brain MRI after therapy. Results: All of the 30 patients had cerebral complications, and 14 patients had at least 2 complications, including 2 cases of hemorrhage, 21 cases of cerebral white matter lesions, 8 cases of cerebral infarction, 16 cases of cerebral atrophy, a case of fungal infection. Conclusion: MRI is the best imaging method for cerebral complications in chemotherapy and transplantation of malignant hematopoiesis. It’s sensitive and can be used to found the changes earlier to guide the treatment.
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Received: 12 January 2015
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Corresponding Authors:
ZHANG Xiao-jin
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