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| CT diagnosis of lung RADS 3-4 lung nodules |
| ZHENG Jiu-lin, WANG Xiao-wu, ZHENG Fu-hu |
| Radiology Department of the Third People’s Hospital, Yueqing Zhejiang 325604, China |
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Abstract Objective: To investigate the value of Lung RADS grading in the screening of lung cancer and the characteristics of malignant nodules, and to improve the diagnostic accuracy. Methods: The findings on baseline screening in 2 580 persons at high-risk for lung cancer were retrospectively analyzed. According to the Lung RADS grading standards, solid and part solid nodules ≥6 mm, ground-glass density nodules ≥20 mm served as a positive value for screening to observe lung cancer positive predictive rate of RADS 3-4 pulmonary nodules, and followed-up to analyze nodule in detail characteristics change. Results: Compared with the screening positive results of the international early lung cancer action program(I-ELCAP), baseline screening overall positive rate was decreased from 22.9%(591/2 580) to 13.8%(357/2 580), lung cancer-positive prediction rate was increased from 6.9%(41/591) to 11.5%(41/357). 8 cases of lung cancer were confirmed by surgery and pathology among 246 cases(Grade 3), 33 cases of lung cancer were diagnosed by pathology among 111 cases(Grade 4A+4B), 41 cases of lung cancer were diagnosed among 357 cases(Grade 3+4), and the number of lung cancer was the same as that of I-ELCAP. Conclusion: Lung RADS grading may be more reasonable to classify the results of lung cancer screening, and reduce the follow-up frequency of patients with low risk, improve the positive rate of lung cancer, combined with the characteristics changes of the nodules, the diagnostic accuracy of pulmonary nodules was greatly improved.
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Received: 03 March 2015
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2015, Vol. 26 
