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| MRI and pathological features of hemangiopericytoma in central nervous system |
| WANG Min, WANG Jian-wei, ZHANG Ling |
| Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China |
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Abstract Objective: To analyze MRI features of hemangiopericytoma(HPC) and correlated with pathological findings． Methods: MRI appearances and pathological features of 15 patients with HPC confirmed by pathology were analyzed retrospectively． Results: The tumor located inside the skull and outside the brain in 15 cases. On MR imaging, the tumors showed lobulated borders, isointensity or slight hypointensity on T1WI and slight hyperintensity on T2WI with cystic degeneration, blood vessel flow void sign and slight perifocal edema. The solid parts of HPC enhanced markedly after contrast agent was injected． Dural tail sign was seen in 2 cases. Immunohistochemical examination performed in 12 cases showed CD34, vimentin expression, and epithelial membrane antigen, cytokeratin, glial fibrillary acidic protein and S-100 showed no expression, Bcl-2 was expressed in 6 cases． Proliferating cell nuclear antigen Ki-67 immunohistochemical staining was expressed in 10 cases, about 10% expressed in 2 cases, 10%~15% expressed in 1 case. Conclusion: HPC in the central nervous system has certain MRI features, which is helpful in improving the accuracy of the preoperative diagnosis．
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Received: 09 July 2013
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2013, Vol. 24 
