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| The value of different MR sequences in the diagnosis of hand-foot-mouth disease complicated with encephalitis |
| FENG Shao-ren, LIN Yun, HU Jin-ping, CHEN Ying, XIONG Shu-hong |
| Affiliated Xinyu Hospital of Nanchang University, Xinyu Jiangxi 338004, China |
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Abstract Objective: To investigate MRI with different sequences in the diagnosis of encephalitis in hand-foot-mouth disease, and correlated with pathology. Methods: In 100 children with hand-foot-mouth disease who had early clinical manifestations of encephalitis underwent axial routine T2WI, T1WI, T2FLAIR, DWI sequences, 56 cases had MRI positive expression, in the 56 cases, 30 cases in the first MRI scan, 13 cases had a second repeat MR examination on the second week(13/30), 17 cases(17/30) had a repeat MR examination on the third week, scanning sequence the same as above. The detection rate was compared between 4 imaging sequences in different periods of disease. Results: In 56 cases there were 147 lesions, the lesion was symmetrical on both sides, MRI showed slightly low signal/low signal on T1WI, and on T2WI, T2FLAIR, DWI showed slightly high signal/high signal mottled shadow, blurred edges, some lesions on T2FLAIR or DWI sequence showed more clearly. T1WI showed 50(50/147), T2WI showed 65(65/147), T2FLAIR showed 120(120/147), DWI showed 109(109/147). DWI and T2FLAIR compared with T2WI, T1WI(P<0.05), T2FLAIR compared with DWI, T1WI compared with T2WI(P>0.05). Thirty cases on repeat MR examination showed the 73 lesions. T1WI showed 55(55/73), T2WI showed 57(57/73), T2FLAIR showed 68(68/73), DWI showed 15(15/73). T2FLAIR compared with DWI(P<0.05), DWI compared with T1WI, T2WI(P<0.05), T2WI compared with T2FLAIR, T1WI compared with T2WI(P>0.05). Conclusion: The combination of T2FLAIR, DWI sequence has important clinical value early diagnosis in for children with hand-foot-mouth disease complicated with encephalitis, T2FLAIR has important clinical value in the diagnosis of children with hand-foot-mouth disease complicated with encephalitis recovery. T2FLAIR, DWI can be used as the preferred sequence for hand-foot-mouth disease complicated with encephalitis.
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Received: 30 October 2013
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2014, Vol. 25 
