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| Diagnosis value of contrast-enhanced ultrasound combined with VTQ technology in the thyroid solid nodules |
| Lanzhou University Second Hospital, Lanzhou 730000, China |
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Abstract Objective: To assessment the diagnosis value of thyroid nodules by the contrast-enhanced ultrasound and the virtual touch tissue quantification(VTQ) of acoustic radiation force impulse. Methods: Sixty-two patients with 96 thyroid solid nodules were enrolled into this prospective study(the final pathology diagnosis was confirmed by thyroidectomy). Analysis of contrast enhancement characteristics, intensity-time curve parameters combination VTQ parameters for differential diagnosis of thyroid benign and malignant nodules. Results: Fifty nodular goiter, 15 adenoma, 31 papillary carcinoma, according to Chi-square test analysis with three types, enhanced degree, enhanced shape, peripheral enhancement had significant statistical difference(P<0.01). In differential benign and malignant nodules aspect, the parameters of RS-Ratio, IMAX-Ratio AUC was relatively larger than others in the time-intensity curve(P<0.01), VTQ parameter SWV and SWV-Ratio AUC was larger than the RS-Ratio, IMAX-Ratio. Conclusion: The contrast-enhanced ultrasound pattern has great value in identification of thyroid nodule pathological type. The VTQ technology has greater value than the intensity-time curve in determination of whether a thyroid nodule was benign or malignant.
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Received: 13 April 2015
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Corresponding Authors:
NIE Fang
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