超声弹性成像评分法与应变率比值法在鉴别诊断#br# 肝脏局灶性病变良恶性中的应用

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Abstract Objective: To evaluate the value of ultrasound elastography(UE) scoring and strain ratio(SR) in differentiating benign and malignant focal liver lesions(FLL). Methods: Conventional ultrasound, ultrasound elastography scoring and SR were performed in 81 patients with 89 FLL, the results were compared with clinical diagnosis. Receiver operating charcteristic(ROC) curves of UE scoring and SR were portrayed, the cut-off points and the areas under the ROC curves(AUCs) were calculated. The sensitivity, specificity, accuracy of conventional ultrasound, UE scoring and SR were calculated, the accuracy of these three methods were evaluated. Results: ①The sensitivity, specificity, accuracy of conventional ultrasound in differentiating benign and malignant FLL was 76.2%, 72.3%, 74.2%. ②The AUC of UE scoring in differentiating benign and malignant FLL was 0.875, the cut-off point was 2.5, the sensitivity, specificity, accuracy of UE scoring was 90.5%, 78.7%, 84.3%. The accuracy of UE scoring in differentiating benign and malignant FLL was higher than conventional ultrasound(P＜0.05). ③The AUC of SR in differentiating benign and malignant FLL was 0.892, the cut-off point was 2.71, the sensitivity, specificity, accuracy of SR was 83.3%, 89.4%, 86.5%. The accuracy of SR in differentiating benign and malignant FLL was higher than conventional ultrasound(P＜0.05). ④The accuracy of UE scoring and SR in differentiating benign and malignant FLL showed no significant difference(P＞0.05). Conclusions: The accuracy of UE scoring and SR in differentiating benign and malignant FLL are higher than conventional ultrasound, they provide new ways to differentiate malignant from benign FLL, UE scoring is in good agreement with SR, there is no significant difference between UE scoring and SR.

Key words： Liver neoplasms Liver diseases Ultrasonography, Doppler, color

Received: 25 May 2015

PACS:	Ｒ735.7
	R575
	Ｒ445.1

Corresponding Authors: HUANG Li-ping

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	ZHENG Shuai
	HUANG Li-ping
	LIU Si-qi
	YANG Hui
	QIAO Jun-pei

Cite this article:

ZHENG Shuai,HUANG Li-ping,LIU Si-qi, et al. The appilication of ultrasound elastography scoring and strain ratio in#br# differentiating benign and malignant focal liver lesions[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2015, 26(11): 794-797.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2015/V26/I11/794

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