CT钙化分型对甲状腺良、恶性结节的诊断价值

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Abstract Objective: To evaluate the diagnostic value of calcified type in benign and malignant thyroid nodules by using CT. Methods: The CT findings of 492 thyroid calcified nodules(including 404 benign nodules and 88 malignant nodules) in 426 cases confirmed by surgery and pathology were retrospectively analyzed. According to the shape of calcification, it is divided into microcalcification, coarse calcification and annular calcification. The distribution of different calcified shapes in benign and malignant nodules, and the sensitivity, specificity, positive predictive value and accuracy of microcalcification in the diagnosis of malignant nodules were analyzed. Results: Among the 492 thyroid calcified nodules, Microcalcification accounted for 25.2%(102/404) and 36.4%(32/88) respectively in the benign and malignant nodules(χ2=4.506, P=0.034), and the sensitivity, specificity, positive predictive value and accuracy of microcalcification in the diagnosis of malignant nodules were 36.4%, 84.4%, 23.9% and 67.9% respectively. Coarse calcification and annular calcification accounted for 61.6%(249/404) and 51.1%(45/88)(χ2=3.311, P=0.0.069), 13.1%(53/404) and 12.5%(11/88)(χ2=0.024, P=0.876) respectively in benign and malignant nodules. Conclusion: In the CT examination, although the microcalcification was more common in malignant thyroid nodules, the sensitivity and specificity were lower, and the distribution of coarse calcification and annular calcification in benign and malignant nodules was not statistically significant, which indicated that, in the CT diagnosis of calcified nodules, other signs should be combined for comprehensive analysis, and the shape could not be regarded as the only evidence to judge whether the nodule was benign or malignant.

Key words： Thyroid nodule Tomography, spiral computed

Received: 08 May 2015

PACS:	Ｒ736.1
	Ｒ814.42

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	Articles by authors
	YANG Hai1
	HAN Zhi-jiang2
	LEI Zhi-kai2
	HU Qun-hui1

Cite this article:

YANG Hai1,HAN Zhi-jiang2,LEI Zhi-kai2, et al. The diagnostic value of CT calcification in benign and malignant thyroid nodules[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2015, 26(12): 861-863.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2015/V26/I12/861

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