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Application of MRI in evaluation on therapeutic efficiency of transcatheter arterial chemoembolization of #br#
hepatocellular carcinoma |
Department of Radiology, the Affiliated Hospital of Luzhou Medical College, Luzhou Sichuan 646000, China |
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Abstract Transcatheter arterial chemoembolization(TACE) is the major means of treatment in patients with unresectable middle-late stage of hepatocellular carcinoma. However, TACE of hepatocellular carcinoma is hard to make the tumor complete necrosis to achieve the purpose of cure, which leads to a high rate of recurrence. We have to take the TACE many times. Therefore, regular follow-up after the TACE, early detection of the cancer survival or recurrence, timely treatment are the important conditions to achieve a good effect. Traditional approaches use tumor size to evaluate tumor response, which has several limitations. At present, DWI and MRS as the representative of functional MRI could provide the information such as the physiological and metabolic changes in the body before the changes of the morphology. They will help to judge curative effect of interventional treatment of hepatocellular carcinoma early. But any single function imaging technology cannot replace the conventional MRI scan and contrast examination completely. Its often requires combination of multiple scan sequences. Combination of multiple imaging techniques of MRI could from various perspective, early, comprehensive analysis and judge whether there is a residual or recurrence of tumor after TACE. With the development of the software and hardware technology of MRI, MRI is expected to become an effective means in evaluation on therapeutic efficiency and follow-up observation of TACE of hepatocellular carcinoma.
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Received: 26 May 2015
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Corresponding Authors:
HAN Fu-gang
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