Abstract Objective: To evaluate the application value of a new modified dual energy image fusion in hepatocellular carcinoma after transcatheter arterial chemoembolization(TACE). Method: Twenty-six hepatocellular carcinoma(HCC) patients after post-TACE underwent normal and three phases dual-energy CT scanning(non-enhanced, arterial, portal, and delayed phases scanning) were enrolled. The arterial phase scans used the dual-energy mode. Two image sets were used to process the data: A, the weighted average image was automatically generated from a linear blending of the data. B, the new double energy fusion was obtained. DSA regarded as the gold standard, we evaluated the feasibility of two image sets, which discriminate contrast enhanced lesions from compact iodized oil accumulations, thereby helping to identify viable lesions around the HCC previously-treated by TACE. Result: DSA revealed 60 lesions in 26 patients, and 45 of them had clear tumor vessel and supply blood. The sensitivity of B(93.3%) was higher than that of A(71.1%)(χ2=8.1, P=0.004), while the specificity of B(93.3%) was insignificantly different with A(66.7%)(χ2=1.5, P=0.221). The B set has a better consistency of DSA(K=0.83, P=0.000). Conclusion: After HCCs with TACE, displaying of iodized oil accumulations and/or enhanced lesion in outside is much better in the new double energy fusion than that in conventional CT protocol.
ZHANG Da-fu,LI Zhen-hui,YANG Guang-jun, et al. Evaluation of hepatocellular carcinoma after TACE by using new dual energy image fusion technique[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(8): 557-561.
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