声触诊组织定量技术（VTQ）在甲状腺良恶性结节鉴别诊断中的#br#
应用价值

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Abstract Objective: To explore the application value of virtual touch tissue quantification(VTQ) in the differential diagnosis of benign and malignant thyroid nodules. Methods: One hundred and thirteen patients with 147 thyroid nodules undergoing thyroid nodules surgery or biopsies after thyroid nodules VTQ examination were retrospectively reviewed. The shears wave velocity(Vs) was measured. The patients were selected from our hospital during Feb. 2013 to Jul. 2015. All cases were divided into benign nodules group(n=52) and malignant nodules group(n=95), according to the pathological results. The Vs of the two groups were detected and statistically analyzed. The ROC curve was drawn, and finally the critical point distinguishing the benign and malignant thyroid nodules Vs was defined. Results: In the 147 focuses, there were 52 benign nodules with the average Vs(2.36±0.44), while 95 malignant nodules with the average Vs(3.65±0.81). There were statistical differences between them(P<0.01). The ROC curve was drawn according to the SWV of the benign malignant nodule. The area under the curve was 0.92±0.02. After analysis, it was concluded that the critical point of the benign and malignant thyroid nodules SWV was 2.96. The corresponding sensitivity, specificity, accuracy, PPV and NPV were 85.3%, 88.5%, 86.4%, 93.1% and 76.7%. Conclusion: VTQ can be regarded as the differential diagnosis basis for benign and malignant thyroid nodules, and has some application value in clinical diagnosis.

Key words： Thyroid nodule Ultrasonography, Doppler, color

Received: 17 December 2015

PACS:	Ｒ581
	Ｒ736.1
	R445.1

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	Articles by authors
	FEI Zheng-dong
	XIE Wei-feng
	CAO Lei
	JIANG Hui
	WANG Hong-hui
	CUI Hong-yan

Cite this article:

FEI Zheng-dong,XIE Wei-feng,CAO Lei, et al. Application value of virtual touch tissue quantification in the differential diagnosis of benign and#br# malignant thyroid nodules[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(9): 612-615.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2016/V27/I9/612

[1]Hoang JK, Lee WK, Lee M, et al. US Features of thyroid malignancy: pearls and pitfalls[J]. Radiographics, 2007, 27(3): 847-860; 861-865.
[2]Cooper DS, Doherty GM, Haugen BR, et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer[J]. Thyroid, 2009, 19(11): 1167-1214.
[3]吕珂，姜玉新，张缙熙，等. 甲状腺结节的超声诊断研究[J]. 中华超声影像学杂志，2003，12（5）：285-288.
[4]Iannuccilli JD, Cronan JJ, Monchik JM. Risk for malignancy of thyroid nodules as assessed by sonographic criteria: the need for biopsy[J]. J Ultrasound Med, 2004, 23(11): 1455-1464.
[5]Nell S, Kist JW, Debray TP, et al. Qualitative elastography can replace thyroid nodule fine-needle aspiration in patients with soft thyroid nodules. A systematic review and meta-analysis[J]. Eur J Radiol, 2015, 84(4): 652-661.
[6]Cho SH, Lee JY, Han JK, et al. Acoustic radiation force impulse elastography for the evaluation of focal solid hepatic lesions: preliminary findings[J]. Ultrasound Med Biol, 2010, 36(2): 202-208.
[7]Yoneda M, Suzuki K, Kato S, et al. Nonalcoholic fatty liver disease: US-based acoustic radiation force impulse elastography[J]. Radiology, 2010, 256(2): 640-647.
[8]Gu J, Du L, Bai M, et al. Preliminary study on the diagnostic value of acoustic radiation force impulse technology for differentiating between benign and malignant thyroid nodules[J]. J Ultrasound, 2012, 31(5): 763-771.
[9]Burke JP, Hay ID, Dignan F, et al. Long-term trends in thyroid carcinoma: a population-based study in Olmsted County, Minnesota, 1935－1999[J]. Mayo Clin Proc, 2005, 80(6): 753－758．
[10]方国恩，李莉. 甲状腺结节的诊断和处理[J]. 中国实用外科杂志，2003，23（3）：135-137.
[11]Ophir J, Cespedes I, Ponnekanti H, et al. Elastography: a quantitative method for imaging the elasticity in biological tissues[J]. Ultrasound Imaging, 1991, 13(2): 1112-1134．
[12]Hou XJ, Sun AX, Zhou XL, et al. The application of Virtual Touch tissue quantification(VTQ) in diagnosis of thyroid lesions: a preliminary study[J]. Eur J Radiol, 2013, 82(5): 797-801.
[13]Unlütürk U, Erdogan MF, Demir O, et al. Ultrasound elastography is not superior to grayscale ultrasound in predicting malignancy in thyroid nodules[J]. Thyroid, 2012, 22(10): 1031-1038.
[14]薛杰，曹小丽，姜宏，等. 甲状腺影像报告与数据系统联合超声弹性成像对甲状腺良恶性结节的诊断价值[J]. 中国医学影像学杂志，2015，23（5）：351-355.
[15]韩蕊君，李凤华，王燕，等. 声触诊组织成像在甲状腺实性结节鉴别诊断中的应用价值[J]. 上海交通大学学报：医学版，2015，35（6）：864-869.
[16]Sporea I, Vlad M, Bota S, et al. Thyroid stiffness assessment by acoustic radiation force impulse elastography(ARFI)[J]. Ultraschall Med, 2011, 32(3): 281-285.
[17]宁春平，徐丽华，房世保，等. 声触诊组织定量技术鉴别甲状腺良恶性结节影响因素的研究[J]. 中华超声影像学杂志，2014，23（7）：594-597.
[18]崔雪梅，陈东风，王少春. 声脉冲辐射力弹性成像在甲状腺实性结节性质鉴别诊断中的价值[J]. 山东医药，2014，54（15）：53-54.
[19]陈越峰，丛淑珍，王煜，等. 超声弹性成像鉴别诊断实性甲状腺良、恶性小结节[J]. 中国医学影像技术，2012，28（2）：252-255.
[20]Zhan J, Jin JM, Diao XH, et al. Acoustic radiation force impulse imaging(ARFI) for differentiation of benign and malignant thyroid nodules—A meta-analysis[J]. Eur J Radiol, 2015, 84(11): 2181-2186.
[21]肖莉莉，赵雅萍，高凌云，等. 声触诊组织量化技术对甲状腺实性小结节良恶性的鉴别诊断价值[J]. 中华超声影像学杂志，2012，21（9）：771-774.