18F-FDG符合线路SPECT/CT显像及99mTc-MDP骨显像对#br#
肺癌骨转移瘤诊断价值的对比研究

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Abstract Objective: To compare the diagnostic efficiency of 18F-FDG coincidence SPECT/CT and 99mTc-MDP bone scintigraphy in the detection of bone metastasis of lung cancer. Methods: A total of 45 patients with lung cancer accepted both 18F-FDG coincidence SPECT/CT imaging and bone scintigraphy sequentially within 2 weeks were retrospectively studied. The differences of diagnostic efficiency on bone metastasis between the two examinations were analyzed. Bone metastases were confirmed by clinical follow-up for at least 6 months. Results: The sensitivity and specificity of 18F-FDG coincidence SPECT/CT for detecting bone metastases of lung cancer were 100% and 97%. The sensitivity and specificity of bone scintigraphy for detecting bone metastases of lung cancer were 92% and 66%. Significant statistical difference was found between 18F-FDG coincidence SPECT/CT imaging and bone scintigraphy for detecting bone metastasis of lung cancer(χ2=4.92, P<0.05). Conclusion: 18F-FDG coincidence SPECT/CT is superior to bone scintigraphy in detecting bone metastasis of lung cancer, meanwhile has the merit to find primary or metastatic tumor outside the bone. 18F-FDG coincidence SPECT/CT is valuable for clinical application.

Key words： Lung neoplasms Bone neoplasms Neoplasms metastasis Tomography, emission-computed, single-photon; Tomography, spiral computed

Received: 06 January 2016

PACS:	Ｒ734.2
	Ｒ738.1
	R817.4

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	Articles by authors
	FANG Sheng-wei
	HAN Su-yang
	ZHANG Pei-pei
	ZHAO Chun-lei

Cite this article:

FANG Sheng-wei,HAN Su-yang,ZHANG Pei-pei, et al. Comparative study on diagnostic value of 18F-FDG coincidence SPECT/CT and 99mTc-MDP bone#br# scintigraphy in bone metastasis of lung cancer[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(9): 649-653.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2016/V27/I9/649

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