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The diagnostic value of dynamic contrast-enhanced MRI in the activity of rheumatoid arthritis lesions of hand |
SUN Yan, ZHANG Bing, JI Tao |
Department of Radiology, Qingdao Municipal Hospital Affiliated to Qingdao University, Qingdao Shandong 266000, China |
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Abstract Objective: To investigate the value of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) in evaluating the activity of rheumatoid arthritis(RA) on early stage. To provide a reliable basis for the reasonable development of RA treatment programs. Methods: The data of wrist DCE-MRI were reviewed in 32 cases of clinically diagnosed RA patients. The differences of the value of hemodynamic parameters, including relative enhancement ratio(RE), early enhancement ratio(REE), were compared in the patients with different activity. Results: ①The RA active group synovial dynamic enhancement curves were rapidly ascending and then reached a stable value. The TIC of remission group showed a slow rise. ②The difference of synovial REE and the RE of the three groups was statistically significant. ③In active RA group, REE and RE was positive correlation with DAS28. Conclusion: The DCE-MRI can provide useful information to evaluate the activity degree and the pathology phase of RA through hemodynamic parameters such as REE and RE. DCE-MRI of RA patients can provide comprehensive evaluation of the progression of RA.
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Received: 07 June 2016
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