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| The value of 18F-FDG PET/CT in the diagnosis of retroperitoneal fibrosis |
| ZHANG Li-ou, SUN Hong-zan, LU Zai-ming |
| Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China |
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Abstract Objective: To investigate the value of 18F-FDG PET/CT imaging in the diagnosis of retroperitoneal fibrosis. Materials and Methods: A retrospective analysis of 18 cases with retroperitoneal fibrosis from January 2013 to October 2016 confirmed by imaging examination with clinical follow-up of more than one year(10 cases) and pathology(8 cases) was performed, including 7 cases in the active phase and 11 cases in the inactive phase with evidence from serum laboratory findings(obviously hige C reactive protein and erythrocyte sedimentation rate). Results: The CT images of 18 patients showed irregular soft tissue masses in retroperitoneum, with unclear boundaries often involving the abdominal aorta, iliac artery, ureter and so on. Five of the 7 patients in the active phase were initially diagnosed, with increased FDG uptake in the masses on PET images. The rest 2 patients had already begun their steroid treatment since 2 and 2.5 months ago respectively, with no significant increase in FDG metabolism on PET images. In the 11 patients with inactive retroperitoneal masses which were initially diagnosed, the FDG metabolism varied. Conclusion: 18F-FDG PET/CT can clearly show the range of retroperitoneal fibrosis by CT, and FDG metabolism on PET is helpful to determine whether the lesion is in the active phase and to evaluate the effect of steroid treatment.
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Received: 24 November 2016
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