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| Different PET/CT diagnosis and pathological types of lung adenocarcinoma presenting as
isolated ground-glass nodules |
| DONG Ke, SHU Jin-er, WANG Li-xia, LOU Jing-jing, WEN Guang-hua |
| Jinhua Hospital of Zhejiang University, Jinhua Zhejiang 321000, China |
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Abstract Objective: To investigate and control analyse the 18F-FDG PET/CT features of lung adenocarcinoma presenting as isolated ground-glass nodules(GGN). Methods: Sixty-eight lung adenocarcinoma presenting as isolated GGN confirmed by surgery pathology were included in this study． The lesions were divided into three groups: precancerous lesions(atypical adenomatous hyperplasia(AAH) and adenocarcinoma in situ(AIS)), microinvasive adenocarcinoma(MIA), invasive adenocarcinoma(IAC).The lesion size, solid portions, morphological feature, metabolism characteristic on the preoperative 18F-FDG PET/CT images in the three groups were analyzed and compared with pathological results． The data were statistically analyzed using SPSS 17.0． Results: The lesion size, solid portions, morphological feature, SUVmax gradually increased from precancerous lesions to IAC． There were statistically significant differences in lesion size and solid portions between the precancerous lesions and MIA groups(P<0.05). There were statistically significant differences in the lesion size, solid portions, morphological feature and metabolism characteristic between MIA and IAC groups(P<0.05, all)． Conclusion: Comprehensive analysis of the 18F-FDG PET/CT image features of GGN, may be helpful for the diagnosis and distinguish diagnosis of precancerous lesions, MIA and IAC．
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Received: 15 February 2017
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