3.0T高分辨磁共振不同成像序列对大脑中动脉粥样硬化斑块成分分析

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Abstract Objective: To investigate the component analysis and display ability of atherosclerotic plaque in the M1 segment of middle cerebral artery by high-resolution MR imaging(HR-MRI) using different sequences, so as to facilitate sequence optimization and diagnosis. Methods: Forty cases of atherosclerotic stenosis in M1 segment of middle cerebral artery were enrolled from September 2015 to December 2016 in our hospital. 3.0T MRI scanner was used to performed the TOF cross section scan, and the location of plaque was determined by 3D-TOF reconstruction, T1WI, T2WI, PDWI and enhanced T1WI were performed perpendicular to the stenotic segment with black-blood MRI technology. The negative and positive cases of lipid core, hemorrhage and calcification of plaque were calculated, and the sensitivity, specificity and K value were analyzed statistically. Results: In 40 cases of atherosclerotic plaque in the M1 segment of middle cerebral artery, there were 32 cases of lipid core plaques, 18 cases of intraplaque hemorrhage, and 22 cases of calcified plaques. Enhanced T1WI that showed lipid core plaques was better, the sensitivity was 100%, specificity was 87.5% and the K value was 0.918. T1WI was the best sequence for demonstrating plaque hemorrhage, the sensitivity was 100%, the specificity was 86.4% and the K value was 0.922. TOF was the best for calcified plaque, the sensitivity was 100%, specificity was 94.4% and the K value was 0.949. Conclusion: Enhanced T1WI has high sensitivity and specificity for displaying lipid core plaques, which is the best display for the lipid core. T1WI and TOF that showed intraplaque hemorrhage was consistent, and TOF could accurately detect plaque calcification. The combination of three sequences of enhanced T1WI, T1WI and TOF can identify the lipid core, hemorrhage and calcification in the plaque.

Key words： Arteriosclerosis Middle cerebral artery Magnetic resonance imaging

Received: 15 June 2017

PACS:	Ｒ743.1
	Ｒ445.2

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	Articles by authors
	FAN Cun-lei
	SUN Yan-hua
	CHEN Shao-wu
	ZHAO Ting-chao
	YANG Ming
	ZHANG Xiao-fei
	LI Fei-long
	CHEN Ya-lei

Cite this article:

FAN Cun-lei,SUN Yan-hua,CHEN Shao-wu, et al. Analysis of atherosclerotic middle cerebral artery plaque components by high-resolution MR imaging[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(4): 234-237.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2018/V29/I4/234

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