3.0T MRI-ASL在脑瘫患儿颈总动脉交感神经网剥脱术前后脑血流量测量的应用

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Abstract Objective: To study the changes of cerebral blood flow(CBF) in children with cerebral palsy before and after common carotid artery adventitial sympathetic nerve net denudation using 3.0T magnetic resonance arterial spin labeling(ASL) technique. Methods: Before and after the operation, 50 patients with spastic unilateral cerebral palsy underwent conventional MRI, DWI, ASL scanning using Philips Achieva/Intera 3.0T MR. The CBF values in bilateral frontal lobe, temporal lobe, parietal lobe and internal capsule area were obtained by MriCloud post-processing workstation. Correlation analysis was performed by paired t test. Results: Before operation, compared with the normal side, the CBF of the affected side in the precentral gyrus, cerebellum, basal ganglia and internal capsule decreased. After operation, compared with the normal side, the cerebral blood flow of the part areas of the affected side was improved, the difference was statistically significant, thalamus cerebral blood flow had no significant difference. After operation, the CBF in the internal capsule area and cerebellum was significantly higher than that before surgery, the difference was statistically significant, the CBF in the cerebral cortex and basal ganglia increased compared with that before operation, but the difference was not statistically significant, the CBF in thalamus was not significantly improved compared with that before operation. Conclusion: The magnetic resonance ASL technology can proved that carotid artery sympathetic nerve net stripping surgery is an effective surgical treatment for cerebral palsy, the operation can effectively improve the CBF, improve cerebral ischemia and hypoxia, and relieve the clinical symptoms.

Key words： Cerebral palsy Magnetic resonance imaging

Received: 14 June 2017

PACS:	Ｒ742.3
	Ｒ445.2

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	Articles by authors
	YU Yang
	WANG Lu-wei
	WANG Yun-ling
	FENG Nan-nan

Cite this article:

YU Yang,WANG Lu-wei,WANG Yun-ling, et al. Application of 3.0T MRI arterial spin labeling in measuring cerebral blood flow before and after carotid sympathetic nerve network denudation in children with cerebral palsy[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(4): 246-249.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2018/V29/I4/246

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