IDEAL-IQ评估健康人BMI与胰腺脂肪定量相关性研究

doi:10.12117/jccmi.2018.07.009

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Abstract Objective: To detect the correlation between BMI of normal healthy people and pancreatic fat quantification by using IDEAL-IQ. Materials and Methods: Thirty-two participants undergoing upper abdomen 1.5T MRI(GE 1.5T Signa HDXT, America) with IDEAL-IQ sequence, were included in this study. Participants were divided into two groups by BMI.Group A(BMI 20.4~23.5 kg/m2) are individuals of normal weight. Group B(BMI 24.0~29.6 kg/m2) are overweighted individuals. Images were uploaded to the ADW4.6 workstation and measured by the software. Three ROIs were placed at the same level in the pancreas uncinate process, head, body and tail, respectively, and the final value of pancreatic fat quantification was the average. The images were double-blindly measured by two radiologists with diagnostic experiences of 3 years and 5 years, respectively. The data were analyzed by SPSS 19.0. Results: Neither age nor gender showed statistical significance between the two groups(P>0.05). The inter-observer agreements were high. The comparison of the average pancreatic fat fraction as well as fat fraction of the pancreatic uncinate process, head and neck, body and tail between the two groups were statistically significant(P<0.05). The fat fraction of uncinate process of the pancreas was weakly correlated with BMI(r=0.396, P<0.01), and the association between the fat fraction of pancreatic head and neck, body and tail and BMI was moderate(r=0.468, 0.641 and 0.648, P<0.01, respectively). No statistical significance was found among the fat fraction of the varied pancreatic locations in the group A(P>0.05), but there was statistical significance in group B(P<0.05). The fat fraction of the body and tail was greater than that of the uncinate process and head and neck(P<0.05). Conclusion: IDEAL-IQ is a convenient and non-invasive method for quantification of pancreatic fat, which has good reproducibility and reliable results. It was found that there were significant differences in fat content of the pancreas between normally weighted and overweighted individuals. For the overweighted, the body and tail are the sensitive sites of fat infiltration in the pancreas.

Key words： Pancreas Fats Body mass index Magnetic resonance imaging

Received: 01 September 2017

PACS:	Ｒ657.5
	Ｒ445.2

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http://www.jccmi.com.cn/EN/10.12117/jccmi.2018.07.009 OR http://www.jccmi.com.cn/EN/Y2018/V29/I7/486

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