|
|
|
| The differential expression of magnetic resonance imaging between male breast cancer and inflammatory granuloma |
| HE Cui-ju1, JIA Yu2, YU Tao1, LUO Ya-hong1 |
1.Department of Radiology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital ＆ Institute,
Shenyang 110042, China; 2.Department of Radiology, Liaoning Cancer Hospital & Institute of
Jinzhou Medical University Postgraduate Cultivation Base, Shenyang 110042, China |
|
|
|
|
Abstract Objective: To investigate the differential diagnosis of MR imaging findings of male breast cancer and inflammatory granuloma. Methods: Confirmed by operation and pathology, 4 cases of male breast cancer and 6 cases of granulomatous mastitis were underwent dynamic contrast-enhanced MR imaging and DWI. Results: The location of the lesions in the two groups were all behind the nipple, and all showed mass lesion. 2 cases of breast cancer were morphologically oval, irregular in 2 cases; clear edge in 2 cases and irregular shape in 2 cases. Internal inhomogeneous enhancement in 2 cases and edge enhancement in 4 cases. 2 cases of skin were involved. The TIC curve showed 3 cases of type Ⅲ, 1 cases of type Ⅱ. The average ADC value was of 0.897×10-3 mm2/s. Inflammatory granuloma were morphologically oval in 2 cases and irregular in 4 cases. There was irregular edge and spiculated in 2 cases. Internal inhomogeneous enhancement in 2 cases and edge enhancement in 4 cases. The TIC curve were all of type Ⅱ. The average ADC value of 0.901×10-3 mm2/s. The edge of the mass were enhanced highly, edge enhancement is higher than that of the center(3 cases) or uneven enhancement(1 cases). There was no enhancement zone (4 cases) in the inflammatory granuloma group. There was no obvious enhancement in the area where high intensity on T2WI. Centrifugal enhanced and the edge of the lesion gradually blurred in the dynamic images(2 cases). Conclusion: For the diagnosis of male breast cancer and inflammatory granuloma lesions, internal enhancement and enhancement curves play an important role in the differential diagnosis of disease in two groups. Breast cancer lesions were of inhomogeneous enhancement or obvious enhancement. Edge enhancement is higher than that of center curve and with TIC curve type Ⅲ. No enhancement area could be observed in granuloma group lesions. Centrifugal enhancement and the edge of lesions gradually blurred could be observed on dynamic image. Enhancement curve were type Ⅱ.
|
|
Received: 01 November 2017
|
|
|
|
|
|
[1]Kuhl CK, Mielcareck P, Klaschik S, et al. Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions[J]. Radiology, 1999， 211(1): 101-110.
[2]American College of Radiology(ACR). Breast imaging reporting and data systm(BI-RADS)[M]. 4th ed. Reston: Am College Radiol, 2003: 1-259.
[3]Nguyen C, Kettler MD, Swirksy ME, et al. Male breast disease: pictorial review with radiologic-pathologic correlation[J]. Radiographics, 2013, 33(3): 763-779.
[4]Korde L, Zujewski JA, Kamin L, et al. Multidisciplinary meeting on male breast cancer: summary and research recommendations[J]. J Clin Oncol, 2010, 28(12): 2114-2122.
[5]Charlot M, Beatrix O, Chateau F, et al. Pathologies of the male breast[J]. Diagn Interv Imaging, 2013, 94(1): 26-37.
[6]Taylor K, Ames V, Wallis M. The diagnostic value of clinical examination and imaging used as part of an age-related protocol when diagnosing male breast disease: an audit of 1141 cases from a single centre[J]. Breast, 2013, 22(3): 268-272.
[7]Lapid O, Siebenga P, Zonderland H. Overuse of male breast imaging[J]. Breast J, 2015, 21(3): 219-223.
[8]Kuwad T, Tozaki M, Harada J. Evaluation of enhancement patterns of using three-dimensional dynamic contrast-enhanced MR imaging in 209 cases of breast cancer[J]. Nippon Igaku Hoshasen Gakkai Zasshi, 2004, 64(8): 544-551.
[9]Teifke A, Behr O, Schmidt M, et al. Dynamic MR imaging of breast lesions: correlation with microvessel distribution pattern and histologic characteristics of prognosis[J]. Radiology, 2006, 239(2): 351-360.
[10]王丽君，汪登斌，费晓春，等. 非哺乳期乳腺炎性病变的MRI表现及其与病理的对照研究[J]. 中华放射学杂志，2014，48（10）：836-840. |
|
|
|
2018, Vol. 29 
