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| Value of MRI in diagnosis of fetal cleft lip and palate |
| ZHU Cheng-feng1, DONG Su-zhen1, LIANG Zhong-hua2, LIU Chun-ling2, WANG Fei2 |
1.Department of Radiology, Shanghai Children's Medical Center, Shanghai JiaoTong University School of Medicine,
Shanghai 200127, China; 2.Department of Radiology, Dalian Obstetrics and Gynecology Hospital,
Affiliated Hospital of Dalian Medical University, Dalian Liaoning 116033, China |
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Abstract Objective: To study the value of MRI in diagnosis of fetal cleft lip and palate． Methods: Imaging materials of 19 cases with fetal cleft lip and palate were retrospectively analyzed. All the pregnant women were examined by ultrasound before MR examination. The imaging protocal included single-shot torbo spin echo in(SSTSE) sequence and T1-weighted imaging fast field echo(T1WI-TFE) sequence. Routine examination of fetal brain, chest and abdomen was performed, focusing on transverse axial and coronal planes of facial region to display any disruption. The width of cleft lip and palate was also measured. Comparative analysis of prenatal MRI, diagnostic ultrasonography and follow-up results was performed. Results: The MRI diagnosis were simple cleft lip(4 cases), and cleft lip and palate(15 cases). The diagnosis assessed after induced labor or postnatal follow-up were in consistent with the diagnosis of prenatal MRI. The prenatal ultrasonographic diagnosis were simple cleft lip(10 cases), simple cleft lip with indefinite cleft palate(6 cases) and cleft lip and cleft palate(3 cases). Conclusions: MRI has a high practical value in the diagnosis of fetal cleft lip and palate, which is an important supplement for prenatal ultrasonographic diagnosis.
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Received: 28 April 2017
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2019, Vol. 30 
