The effect of high signal vascular sign on cerebral blood flow and prognosis in acute cerebral infarction
GAO Li-zhen1, QIAN Yu-quan1, ZHANG Bing2, LIU Jun3
1.Department of Imaging, Taikang Tongji(Wuhan) Hospital, Wuhan 433000, China;
2.Department of Imaging, The Second Affliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China;
3.Department of Imaging, Tianjin People's Hospital, Tianjin 300121, China
Abstract Objective: To investigate the cerebral parenchymal blood perfusion status in hyperintense vessel sign(HVS) area on fluid attenuated inversion recovery(FLAIR) sequence during acute cerebral infarction and to evaluate the relationship between HVS change and short-term prognosis. Methods: Sixty-seven patients with acute cerebral infarction in middle cerebral artery(MCA) blood supply area without thrombolysis treatment were divided into HVS negative group and HVS positive group according to the presence of HVS. Cerebral blood volume(CBF) value of “HVS-DWI” mismatch area or around the infarct was obtained by 3D-pulsed arterial spin labeling scan. The relationship between HVS and NIHSS score, infarction area, rCBF was analyzed. The relationship between HVS and the change of the disease was observed in 13 HVS positive patients. Results: HVS sign was observed 38(56.7%) of 67 enrolled cases. NIHSS score and the infarction area of HVS positive group were higher than those of HVS negative group(P<0.05). The rCBF value of mismatched areas of “HVS-DWI” was decreased(P=0.012<0.05). Among the re-examination patients, there was no significant change in the range of HVS in 5 patients, with new infarction and progressive disease. Conclusion: In acute cerebral infarction, the appearance of HVS suggests severe neurological dysfunction and large infarction area, and the cerebral parenchymal blood flow in the“HVS-DWI” mismatched areas is hypoperfusion, and the persistence of HVS needs to be vigilant for new infarction.
GAO Li-zhen1,QIAN Yu-quan1,ZHANG Bing2, et al. The effect of high signal vascular sign on cerebral blood flow and prognosis in acute cerebral infarction[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(5): 305-309.
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2020, Vol. 31 
