|
|
|
| Imaging findings and clinicopathological features of ovarian germ cells malignancies in children and adolescents |
| HU Yue-lin, GAO Qiu, SHI Quan, WANG Rui, ZHANG Ming-jie, CHEN Zhen |
| Guangzhou Women and Children’s Medical Centre, Guangzhou 510623, China |
|
|
|
|
Abstract Objective: To analyze the imaging findings and pathological findings of ovarian germ cell malignancies in children and adolescents. Methods: Twenty-seven patients with ovarian malignant germ cell tumors confirmed by pathology were retrospectively analyzed. The imaging features were analyzed and compared with pathology. Results: Ten cases of endodermal sinus tumor, 5 cases of immature teratoma, 6 cases of dysgerminoma, 5 cases of mixed germ cell tumor, one case of bilateral ovary were dysgerminoma and mixed germ cell tumor, various ovary malignant germ cell tumors have their imaging and clinical features. Conclusion: The CT and MR findings of ovarian malignant germ cell tumors in children and adolescents have certain characteristics. Combined with their clinical features and tumor markers examination, qualitative diagnosis can be made.
|
|
Received: 08 October 2019
|
|
|
|
|
|
[1]周锦英，卞丽红. 儿童及青少年卵巢恶性肿瘤[J]. 国际妇产科学杂志，2015，42（l）：17-20.
[2]Kathleen FB, Michael CC, Leonidas GK, et al． A population based analysis of 1037 malignant ovarian tumors in the pediatric population[J]． J Surg Res, 2009, 156(1)： 45-49．
[3]Akyuz C, Varan A, Buyukpamukcu N, et al． Malignant ovarian tumors in children: 22 years of experience at a single institution[J]． J Pediat Hematol Oncol, 2000, 22(5): 422-427．
[4]张丹晔，谭明子，王慧敏，等． 儿童卵巢恶性肿瘤21例临床分析[J]. 现代肿瘤医学，2013，21（6）：1355-1359．
[5]Lakshmanan M, Gupta S, Kumar V, et al． Germ cell tumor ovary: an institutional experience of trestment and survival outcomes[J]. Indian J Surg Oncol, 2018, 9(2): 215.
[6]Yamaoka T, Togashi K， Koyama T, et al. Yolk sac tumor of the ovary: radiologic-pathologic correlation in four cases[J]. J Comput Assist Tomogr, 2000, 24(4): 605-609.
[7]张红丽，徐亮，许建铭，等. 卵巢未成熟畸胎瘤的MRI征象及临床病理分析[J]. 中国医学影像学杂志，2016，27（4）：275-277．
[8]容豫，王金清，郭应坤，等. 卵巢恶性畸胎瘤的CT表现[J]. 中国医学影像学杂志，2019，27（4）：316-319．
[9]Parkinson CA, Hatcher HM, Ajithkumar TV. Management of malignant ovarian germ cell tumors[J]. Obstet Gynecol Surv, 2011, 66(8): 507-514.
[10]郭亚茹，鲁艳明. 卵巢恶性生殖细胞肿瘤的研究进展[J]. 肿瘤研究与临床，2019，31（8）：562-565．
[11]Pauniaho SL, Salonen J, Helminen M, et al. The incidences of malignant gonadal and extragonadal germ cell tumors in males and females: a population-based study covering over 40 years in Finland[J]. Cancer Causes Control, 2012, 23(9): 1921-1927.
[12]Soheila A, Iman M, Azadeh A, et al. Ovarian malignant mixed germ cell tumor: a case of unusual presentation as molar pregnancy[J]. J Reprod Infertile, 2016, 17(2): 133-136.
[13]陆云峰，肖智博，黄扬，等. 卵巢无性细胞瘤的CT及MRI诊断[J]. 中国医学影像学杂志，2015，23（8）：618-621. |
|
|
|
