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| Analysis of super bone imaging in 58 cases |
| ZENG Ling-peng1, LUO Kan-ying2, ZHANG Qing1, ZHANG Qing1 |
1. Department of Nuclear Medical, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China;
2. Department of Vascular Mammary, Jiangxi Provincial People’s Hospital, Nanchang 330006, China |
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Abstract Objective: To investigate the etiology, imaging characteristics of super bone imaging, and the differences in age, alkaline phosphatase(ALP), and serum calcium levels among patients with different etiology. Methods: The clinical data of 58 cases with super bone imaging were retrospectively analyzed. According to different causes, patients with malignant bone metastases were divided as metastasis group, and metabolic bone disease patients were divided as metabolome group, then the differences in age, ALP and serum calcium levels between the two groups were statistically analyzed. According to the characteristics of super bone imaging images, it was divided into two types: uniform symmetry(type Ⅰ) and focal scattered distribution type(type Ⅱ). Results: The positive rate of super bone imaging was 0.32%(58/18 406), of which bone metastases were the most common, followed by metabolic bone disease. Uniform symmetrical images accounted for 58.6%(34/58), and bone metastases and metabolic bone disease accounted for 44.8%(26/58) and 13.8%(8/58) among those patients. The average age and the ALP level of the patients in the metastatic group were higher than that in the metabolome group, while the blood calcium level of patients in the metabolome group was higher than that in the metastatic group, the difference was statistically significant(P<0.05). Conclusion: Bone metastases are the most common causes of super bone imaging. Both bone metastasis and metabolic bone disease can be characterized by super bone imaging with uniform symmetry. Age, ALP and serum calcium are valuable in the identification of the two etiologies of super bone imaging.
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Received: 24 October 2019
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[1]杨爱民，王淑霞，邓惠兴，等. 放射性核素骨显像“超级影像”的特点[J]. 实用放射学杂志，2007，23（2）：236-237.
[2]Osmond JD, Pendergrass HP, Potsaid MS. Accuracy of 99mTC-diphosphonate bone scans and roentgenograms in the detection of prostate, breast and lung carcinoma metastases[J]. Am J Roentgenol Radium Ther Nucl Med, 1975, 125(4): 972-977.
[3]黄建敏，潘莉萍，刘晓梅，等. 骨扫描中的超级骨显像[J]. 中国临床医学影像杂志，2009，20（9）：711-713.
[4]Constable AR, Cranage RW. Recognition of the superscan in prostatic bone scintigraphy[J]. Br J Radiol 1981, 54(638): 122-125.
[5]Manohar PR, Rather TA, Khan SH, et al. Skeletal Metastases Presenting as Superscan on Technetium 99m Methylene Diphosphonate Whole Body Bone Scintigraphy in Different Type of Cancers: A 5-Year Retro-prospective Study[J]. World J Nucl Med, 2017, 16(1): 39-44.
[6] Pour MC, Simon-Corat Y, Horne T. Diffuse increased uptake on bone scan: super scan[J]. Semin Nucl Med, 2004, 34(2): 154-156.
[7]解朋，建敏，潘莉萍，等. 骨髓纤维化症骨显像表现为超级骨显像1例[J]. 中国临床医学影像杂志，2011，22（1）：73-74.
[8]任静芸，李燕，罗亚平. 超级骨显像的鉴别诊断一例[J]. 中华核医学与分子影像杂志，2019，39（1）：39-40.
[9]Harshman LK, Latifi HR, Griffeth LK. Visualization of Discrete Sacral Foramina as an Ancillary Sign of Superscan[J]. Clin Nucl Med, 2011, 36(1): 21-24.
[10]黄建敏，潘莉萍，刘晓梅，等. 骨扫描中的超级骨显像[J]. 中国临床医学影像杂志，2009，20（9）：711-713.
[11]Fang J, Xu Q. Differences of osteoblastic bone metastases and osteolytic bone metastases in clinical features and molecular characteristics[J]. Clin Transl Oncol, 2015, 17(3): 173-179.
[12]刘志武，李莉，谭榜云，等. 血清ODF和OCIF及Ca ALP水平在肺癌骨转移中临床研究[J]. 西部医学，2014，26（2）：239-241.
[13]Tandon PK, Rizvi AA. Hypocalcemia and parathyroid function in metastatic prostate cancer[J]. Endocrine Practice, 2005, 11(4): 254-258.
[14]姜艳，柴晓峰，孟迅吾，等. 以成骨性骨转移致低钙血症为首发表现的前列腺癌[J]. 中华骨质疏松和骨矿盐疾病杂志，2010，3（4）：298-301.
[15]宋玉文，李梅. 多种代谢性骨病对患者生活质量的影响[J]. 中华骨质疏松和骨矿盐疾病杂志，2018，11（4）：403-407.
[16]李悦芃，王芬，茅江峰，等. 全身疼痛-高碱性磷酸酶血症-超级骨显像：恶性肿瘤骨转移一例[J]. 中华内分泌代谢杂志，2017，33（8）：696-698. |
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